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Longer titles found: Germinal center B-cell like diffuse large B-cell lymphoma (view)

searching for Germinal center 102 found (174 total)

CD320 (528 words) [view diff] case mismatch in snippet view article find links to article

"Identification of a Human Follicular Dendritic Cell Molecule That Stimulates Germinal Center B Cell Growth". J. Exp. Med. 191 (6): 1077–84. doi:10.1084/jem.191

Adenosine deaminase (2,982 words) [view diff] exact match in snippet view article find links to article

biosynthetic process purine ribonucleoside monophosphate biosynthetic process germinal center B cell differentiation liver development lung alveolus development

MCM3 (1,553 words) [view diff] exact match in snippet view article find links to article

nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication"

MAP4K5 (937 words) [view diff] exact match in snippet view article find links to article

kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related". J. Immunol. 163 (6). UNITED STATES: 3279–85. doi:10

CDH17 (780 words) [view diff] exact match in snippet view article find links to article

integrin activation by cell surface receptor linked signal transduction germinal center B cell differentiation B cell differentiation adherens junction organization

MEF2C (1,895 words) [view diff] exact match in snippet view article find links to article

specification regulation of dendritic spine development regulation of germinal center formation roof of mouth development cell differentiation chondrocyte

Naive B cell (301 words) [view diff] exact match in snippet view article find links to article

receptor in B-cell lymphoproliferative disorders deriving from naive, germinal center, and memory B lymphocytes". Clin. Cancer Res. 10 (1 Pt 1): 144–54.

Primary testicular diffuse large B-cell lymphoma (2,625 words) [view diff] exact match in snippet view article find links to article

malignant B-cells are termed "activated B-cells" to distinguish them from "germinal center B-cells". While DLBCL may involve either type of B-cell, the various

MAP4K2 (936 words) [view diff] exact match in snippet view article find links to article

protein kinase in human B lymphocytes. Preferential localization in the germinal center". The Journal of Biological Chemistry. 269 (24): 16802–9. doi:10

B-cell activating factor (3,099 words) [view diff] exact match in snippet view article find links to article

SL (October 2006). "Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production". Seminars in Immunology. 18 (5):

Garnett H. Kelsoe (616 words) [view diff] exact match in snippet view article find links to article

collaborators have made a number of contributions to understanding the germinal center response, a transient cellular complex that supports rapid mutation

CD69 (2,279 words) [view diff] case mismatch in snippet view article find links to article

Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate". Immunity.

Gene expression profiling in cancer (2,260 words) [view diff] exact match in snippet view article find links to article

expression profiling techniques to stratify DLBCL to two subtypes: germinal center B-like DLBCL and activated B-like DLBCL. The authors developed custom

Follicular dendritic cell sarcoma (2,551 words) [view diff] exact match in snippet view article find links to article

lymphoid follicles and have an integral role in regulation of the germinal center reaction and present antigens to B cells. Most cases of FDCS develop

RC3H1 (642 words) [view diff] exact match in snippet view article find links to article

process regulation of germinal center formation posttranscriptional regulation of gene expression negative regulation of germinal center formation negative

ADAM17 (2,495 words) [view diff] exact match in snippet view article find links to article

regulation of cell migration wound healing, spreading of epidermal cells germinal center formation tumor necrosis factor-mediated signaling pathway negative

Protein kinase N1 (1,783 words) [view diff] exact match in snippet view article find links to article

vesicle protein-containing complex Biological process regulation of germinal center formation negative regulation of protein phosphorylation renal system

TRAF2 (3,427 words) [view diff] exact match in snippet view article find links to article

required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production". Nature Immunology

ADAMDEC1 (415 words) [view diff] exact match in snippet view article find links to article

important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]. "Entrez Gene: ADAM-like, decysin

PDCD10 (1,340 words) [view diff] exact match in snippet view article find links to article

and functions as part of a larger signaling complex that includes germinal center kinase III. Specifically, PDCD10 has been shown to interact with RP6-213H19

MAP4K4 (3,301 words) [view diff] exact match in snippet view article find links to article

kinase 4 (MAP4K4) – also known as hepatocyte progenitor kinase-like/germinal center kinase-like kinase (HGK) and Nck-interacting kinase (NIK) – is an enzyme

Eugene C. Butcher (1,346 words) [view diff] exact match in snippet view article find links to article

2001; 2: 9: 876-81 Arnold CN, Campbell DJ, Lipp M, Butcher EC "The germinal center response is impaired in the absence of T cell-expressed CXCR5." Eur

NFKB2 (1,287 words) [view diff] exact match in snippet view article find links to article

cytokine regulation of transcription, DNA-templated rhythmic process germinal center formation ageing extracellular matrix organization negative regulation

UNC13D (974 words) [view diff] exact match in snippet view article find links to article

natural killer cell degranulation regulation of mast cell degranulation germinal center formation positive regulation of exocytosis positive regulation of

STK24 (1,383 words) [view diff] exact match in snippet view article find links to article

two groups - p21-activated kinase and germinal center kinase (GCK) families. STK24 belongs to the germinal center kinase (GCK) III subfamily of sterile

MAP3K1 (3,182 words) [view diff] exact match in snippet view article find links to article

required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production". Nature Immunology

FBXO11 (1,160 words) [view diff] no match in snippet view article find links to article

FBXO11-mediated BCL6 degradation has been shown to contribute to abnormal germinal-center formation and tumorigenesis. The Caenorhabditis elegans DRE-1/FBXO11

FOXJ1 (1,996 words) [view diff] exact match in snippet view article find links to article

immunoglobulin brain development humoral immune response negative regulation of germinal center formation central tolerance induction negative regulation of NF-kappaB

TNIK (875 words) [view diff] exact match in snippet view article find links to article

including cancer, neurological disorders, and inflammatory conditions. Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase

CD278 (1,648 words) [view diff] exact match in snippet view article find links to article

agreement with reduced Th2 responses, ICOS-/- mice expressed reduced germinal center formation and IgG1 and IgE antibody titers in response to immunization

CD23 (1,729 words) [view diff] exact match in snippet view article find links to article

cells using immunohistochemistry but is minimally expressed by benign germinal center B cells. In contrast to neoplastic mantle cells (which are negative

Complement receptor 2 (1,829 words) [view diff] exact match in snippet view article find links to article

PMID 18713965. Donius LR, Handy JM, Weis JJ, Weis JH (July 2013). "Optimal germinal center B cell activation and T-dependent antibody responses require expression

Michael Meyer-Hermann (866 words) [view diff] exact match in snippet view article find links to article

Michael Meyer-Hermann, Michael L. Dustin, Michel C. Nussenzweig: Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable

TNFAIP3 (1,971 words) [view diff] exact match in snippet view article find links to article

intracellular membrane-bounded organelle Biological process regulation of germinal center formation positive regulation of hepatocyte proliferation negative

CRTC2 (1,105 words) [view diff] exact match in snippet view article find links to article

Herling M, Jones D, Wall R, Teitell MA (June 2007). "TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and

CD83 (2,188 words) [view diff] case mismatch in snippet view article find links to article

Gläsner J, et al. (May 2016). "CD83 Modulates B Cell Activation and Germinal Center Responses". Journal of Immunology. 196 (9): 3581–3594. doi:10.4049/jimmunol

BAFF receptor (1,207 words) [view diff] exact match in snippet view article find links to article

SL (October 2006). "Impact of the BAFF/BR3 axis on B cell survival, germinal center maintenance and antibody production". Seminars in Immunology. 18 (5):

Chromosome 21 (3,068 words) [view diff] no match in snippet view article find links to article

MAP3K7CL: encoding MAP3K7 C-terminal-like protein MCM3AP: encoding germinal-center associated nuclear protein MIR155 producing microRNA miR-155 MIR3648:

Jason Cyster (1,199 words) [view diff] exact match in snippet view article find links to article

approaches to uncover mechanisms of: Cell migration and chemoattraction Germinal center formation and affinity maturation Egress of lymphocytes from lymphoid

Nucleoside-modified messenger RNA (2,522 words) [view diff] exact match in snippet view article find links to article

"Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses". The Journal of Experimental Medicine. 215 (6): 1571–1588

CD99 (2,366 words) [view diff] exact match in snippet view article find links to article

women. In patients with diffuse large B-cell lymphoma (DLBCL) with the germinal center B-cell (GCB, classified according to the Muris algorithm) subtype,

BCL3 (2,570 words) [view diff] exact match in snippet view article find links to article

DNA-templated T-helper 2 cell differentiation antimicrobial humoral response germinal center formation response to virus DNA damage response, signal transduction

Integrin beta 7 (1,414 words) [view diff] exact match in snippet view article find links to article

patches inhibits the increase in CD38 expression associated with the germinal center reaction". Journal of Immunology. 166 (4): 2179–85. doi:10.4049/jimmunol

ICOSLG (2,189 words) [view diff] exact match in snippet view article find links to article

ICOS gene in mice. ICOS deficient mice are characterized by impaired germinal center formation, have a profound defect in isotype class switching in T cell-dependent

Interleukin 7 (1,676 words) [view diff] exact match in snippet view article find links to article

cells produce interleukin-7: a potential role for interleukin-7 in the germinal center reaction". Eur. J. Immunol. 26 (10): 2541–4. doi:10.1002/eji.1830261040

MAP4K1 (665 words) [view diff] exact match in snippet view article find links to article

Groffen J, Feng GS, Blenis J, Tan TH, Feller SM (Oct 1998). "The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for

Common variable immunodeficiency (3,371 words) [view diff] exact match in snippet view article find links to article

(CD19,CD81, CD21) Impaired BCR signaling IL-21R and IL-21 Impaired germinal center formation, impaired class-switch process and plasma cell differentiation

FDC-SP (1,089 words) [view diff] case mismatch in snippet view article find links to article

(2007). "Follicular Dendritic Cell Secreted Protein (FDC-SP) Regulates Germinal Center and Antibody Responses". The Journal of Immunology. 178 (12): 7859–7867

PDCD2 (658 words) [view diff] exact match in snippet view article find links to article

repressed by BCL6, a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects

CD86 (3,326 words) [view diff] exact match in snippet view article find links to article

overlapping, critical roles in immunoglobulin class switching and germinal center formation". Immunity. 6 (3): 303–13. doi:10.1016/s1074-7613(00)80333-7

NRK (gene) (401 words) [view diff] exact match in snippet view article

phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family". Exp. Cell Res. 287 (2): 219–27. doi:10.1016/S0014-4827(03)00136-8

DTX1 (714 words) [view diff] exact match in snippet view article find links to article

"Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells". Molecular Immunology. 39 (13): 791–9. doi:10.1016/S0161-5890(03)00002-6

METAP2 (3,034 words) [view diff] exact match in snippet view article find links to article

S (2002). "High expression of methionine aminopeptidase type 2 in germinal center B cells and their neoplastic counterparts". Lab. Invest. 82 (7): 893–901

Complement receptor 1 (2,908 words) [view diff] exact match in snippet view article find links to article

PMID 18713965. Donius LR, Handy JM, Weis JJ, Weis JH (July 2013). "Optimal germinal center B cell activation and T-dependent antibody responses require expression

Teratoma (5,152 words) [view diff] exact match in snippet view article find links to article

(March 2018). "N-methyl-D-aspartate receptor antibody production from germinal center reactions: Therapeutic implications". Annals of Neurology. 83 (3):

MINK1 (665 words) [view diff] exact match in snippet view article find links to article

Misshapen-like kinase 1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases

Free-radical theory of aging (3,124 words) [view diff] exact match in snippet view article find links to article

protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis". Free Radical

BCL11A (1,657 words) [view diff] exact match in snippet view article find links to article

splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells". Molecular Cancer. 5 18. doi:10.1186/1476-4598-5-18. PMC 1526750

MST4 (865 words) [view diff] exact match in snippet view article find links to article

Pandey A (2002). "Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties". J. Biol

OXSR1 (774 words) [view diff] exact match in snippet view article find links to article

(2004). "Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily". J. Biol. Chem. 279 (12): 11129–36. doi:10.1074/jbc

BCL-6 corepressor (1,146 words) [view diff] exact match in snippet view article find links to article

BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts

RASGRP2 (682 words) [view diff] exact match in snippet view article find links to article

PMID 24958846. Kedra D, Seroussi E, Fransson I, et al. (1997). "The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity

Granulocyte colony-stimulating factor (3,832 words) [view diff] exact match in snippet view article find links to article

in vitro by human B-lineage lymphocytes is a distinctive marker of germinal center cells". Journal of Immunology. 153 (7): 2868–2877. doi:10.4049/jimmunol

NFKBID (841 words) [view diff] exact match in snippet view article find links to article

inhibitor of the NF-κB cascade. By its functions, including promotion of germinal center reactions and its requirement in immunosuppressive regulatory T cell

SLK (gene) (969 words) [view diff] exact match in snippet view article

into three categories. the most important p21-activated kinase (PAK), germinal center kinases (GCK) and Pleckstrin homology domain containing PAK (PHPAK)

SH3GL2 (1,180 words) [view diff] exact match in snippet view article find links to article

"Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase". J. Biol. Chem. 276 (31): 28913–9. doi:10.1074/jbc

RNF20 (865 words) [view diff] exact match in snippet view article find links to article

Eisen MB, et al. (2000). "Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas"

Sunda Arc (3,689 words) [view diff] exact match in snippet view article find links to article

for further usages including producing electricity. Java is also a germinal center for supplying gold and copper in which the occurrences of these low-sulfidation

MAP4K3 (643 words) [view diff] exact match in snippet view article find links to article

Chen DY, Chuang HC, Lan JL, Chen YM, Hung WT, Lai KL, Tan TH (2012). "Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset

N1-Methylpseudouridine (1,512 words) [view diff] exact match in snippet view article find links to article

"Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses". The Journal of Experimental Medicine. 215 (6): 1571–1588

TANK (gene) (1,420 words) [view diff] exact match in snippet view article

N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathway". Molecular and Cellular Biology. 19 (10): 6665–72.

Meinrad Busslinger (1,031 words) [view diff] exact match in snippet view article find links to article

functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development". Retrieved 2019-01-08. "Essential

Günter Burg (1,711 words) [view diff] no match in snippet view article find links to article

Burg, G.; Rajewsky, K.; Küppers, R., (1999). Identification of common germinal-center B-cell precursors in two patients with both Hodgkin's disease and non-Hodgkin's

Serpin (14,394 words) [view diff] exact match in snippet view article find links to article

Pascual V (October 2000). "Identification of centerin: a novel human germinal center B cell-restricted serpin". European Journal of Immunology. 30 (10):

KMT2D (3,946 words) [view diff] exact match in snippet view article find links to article

AB, Bansal M, et al. (October 2015). "Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis". Nature Medicine.

ALS2CR2 (789 words) [view diff] exact match in snippet view article find links to article

(April 2003). "Identification and characterization of a novel Ste20/germinal center kinase-related kinase, polyploidy-associated protein kinase". The Journal

Interleukin-17A (6,473 words) [view diff] exact match in snippet view article find links to article

17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice". Nature Immunology. 9 (2): 166–175

TMEM156 (903 words) [view diff] exact match in snippet view article find links to article

FAM92B-family with sequence similarity 92, member B NUGGC-nuclear GTPase, germinal center associated plays a role as replication-related GTPase CEACAM21-carcinoembryonic

FCRL3 (1,917 words) [view diff] exact match in snippet view article find links to article

markers. It is expressed in relatively low levels on naïve B cells, germinal center B cells, memory B cells, marginal zone B cells and peripheral blood

CRKL (3,165 words) [view diff] exact match in snippet view article find links to article

Groffen J, Feng GS, Blenis J, Tan TH, Feller SM (October 1998). "The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for

T cell receptor revision (1,333 words) [view diff] no match in snippet view article find links to article

CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions". Proceedings of the National Academy of Sciences of the

Adapter molecule crk (2,943 words) [view diff] exact match in snippet view article find links to article

Adermann K, Groffen J, Feng GS, Blenis J, Tan TH, Feller SM (1998). "The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for

P110δ (2,517 words) [view diff] exact match in snippet view article find links to article

"Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction". Journal of Immunology. 185 (7): 4042–52. doi:10.4049/jimmunol

DNA methylation (13,391 words) [view diff] exact match in snippet view article find links to article

stages. The largest methylation difference is between the stages of germinal center B cells and memory B cells. Furthermore, this study showed that there

Herpes simplex research (8,961 words) [view diff] exact match in snippet view article find links to article

HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing

HHV-8-associated MCD (2,206 words) [view diff] exact match in snippet view article find links to article

Castleman's Disease showing LANA-1 positive lymphoblasts in a regressed germinal center and mantle zone. LANA-1 stain. Specialty Hematology, immunology, infectious

EZH2 (5,395 words) [view diff] no match in snippet view article find links to article

EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin". Nature Genetics. 42 (2): 181–185. doi:10.1038/ng.518. PMC 2850970

List of human clusters of differentiation (499 words) [view diff] no match in snippet view article find links to article

platelets. CD10 a type II transmembrane protein found on pre-B cells, germinal-center B cells, some neutrophils, kidney cells, T-cell precursors, and epithelial

Sidonia Făgărășan (490 words) [view diff] exact match in snippet view article find links to article

(24 July 2011). "Foxp3+ follicular regulatory T cells control the germinal center response". Nature medicine. 17 (8): 975–982. doi:10.1038/NM.2425. ISSN 1078-8956

Ari Melnick (539 words) [view diff] exact match in snippet view article find links to article

(2018-01-15). "AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis". Nature Communications. 9 (1): 222. Bibcode:2018NatCo

Hendrik Streeck (1,952 words) [view diff] exact match in snippet view article find links to article

helper (Tfh) cells can drive protective antibody responses during the germinal center reaction. Further research areas of the institute include understanding

GRB2 (9,409 words) [view diff] exact match in snippet view article find links to article

Groffen J, Feng GS, Blenis J, Tan TH, Feller SM (October 1998). "The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for

Mammalian SWI/SNF (BAF) complex (10,609 words) [view diff] exact match in snippet view article

Burkitt lymphoma are subtypes of non-Hodgkin lymphoma originating from germinal center B cells; while DLBCL is the most common, Burkitt lymphoma is the most

Martin Turner (scientist) (1,886 words) [view diff] case mismatch in snippet view article

Phosphoinositide 3-Kinase Activity in T Cells Regulates the Magnitude of the Germinal Center Reaction. J. Immunol. 185: 4042-4052 PMID 20826752. Selected as a highlight

T cell/histiocyte-rich large B-cell lymphoma (2,173 words) [view diff] case mismatch in snippet view article find links to article

Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma". Immunity. 51 (3):

PRDM1 (2,688 words) [view diff] exact match in snippet view article find links to article

can either differentiate into a short-lived plasma cell or into a germinal center B cell after receiving proper activation and co-stimulation. BLIMP-1

Fibrin-associated diffuse large B-cell lymphoma (1,904 words) [view diff] exact match in snippet view article find links to article

proliferation and are activated rather than non-activated B-cells (i.e. germinal center B-cells or unclassifiable B-cells) as identified by immunohistochemical

Porcine parvovirus (8,982 words) [view diff] exact match in snippet view article find links to article

8-week-old pigs, examined by IF microscopy (×312.5). (A) Viral antigen in germinal center, tonsil. (B) Viral antigen in osteogenic layer of periosteum, rib:

Moon Nahm (1,820 words) [view diff] exact match in snippet view article find links to article

antigen come together, and showed the need of lymphotoxin cytokine for germinal center formation with David D. Chaplin MD PhD. His research has been described

Diffuse large B-cell lymphoma associated with chronic inflammation (3,708 words) [view diff] exact match in snippet view article find links to article

far more aggressive than those caused by other B-cell types, i.e. germinal center B-cells (GBC) or unclassifiable B-cells. The ABC basis of DLBCL-CI

LL-100 panel (4,749 words) [view diff] exact match in snippet view article find links to article

B-cell lymphoma: higher expression of ZAP70 and PKC-beta II in the non-germinal center group and poor survival in patients deficient in nuclear PTEN". Leukemia

Dario Angelo Alberto Vignali (3,633 words) [view diff] exact match in snippet view article find links to article

HPV-negative tumors, with HPV+ tumors showing increased presence of germinal center B cells and tertiary lymphoid structures, correlated with better survival