Find link

language:

Find link is a tool written by Edward Betts.

searching for CDKN2A 58 found (102 total)

alternate case: cDKN2A

P14arf (2,857 words) [view diff] exact match in snippet view article find links to article

suppressor, ARF, p14ARF) is an alternate reading frame protein product of the CDKN2A locus (i.e. INK4a/ARF locus). p14ARF is induced in response to elevated

CDKN2BAS (1,125 words) [view diff] exact match in snippet view article find links to article

spliced product is a 3834bp RNA. It is located within the p15/CDKN2B-p16/CDKN2A-p14/ARF gene cluster, in the antisense direction. Single nucleotide polymorphisms

Genetic causes of type 2 diabetes (2,339 words) [view diff] exact match in snippet view article find links to article

Genes such as CDKN2A, CDKN2B, and HNF1B exhibit increase the risk phenotype with SNPs in their 3' UTR miRNA binding sites. As CDKN2A and B regulate the

COSMIC cancer database (979 words) [view diff] exact match in snippet view article find links to article

(tissue) summary page provides lists of mutated genes. The figure shows the CDKN2A gene, which is a tumor suppressor that leads to cancer when it is inactivated

Mir-340 microRNA precursor family (386 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

Mir-345 microRNA precursor family (538 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

CDKN2B (1,386 words) [view diff] exact match in snippet view article find links to article

CDKN2B gene in humans. This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated, deleted, or disregulated in a wide

Mir-455 microRNA precursor family (760 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

Oropharyngeal cancer (1,950 words) [view diff] exact match in snippet view article find links to article

Asbestos-related diseases); Certain genetic changes including: P53 mutation and CDKN2A (p16) mutations; Poor nutrition; Plummer–Vinson syndrome. Erythroplakia;

Mir-885 microRNA precursor family (820 words) [view diff] exact match in snippet view article find links to article

M.; Salmenkivi, K.; Bagwan, I.; Nicholson, A. G.; Knuutila, S. (2009). "CDKN2A,NF2, andJUNare dysregulated among other genes by miRNAs in malignant mesothelioma-A

Erica Golemis (710 words) [view diff] exact match in snippet view article find links to article

TP53 and CDKN2A in order to show that patterns of hotspot mutations in TP53 differed depending on the presence or absence of a co-occurring CDKN2A mutation

Cyclin-dependent kinase inhibitor protein (1,169 words) [view diff] exact match in snippet view article find links to article

Protein Gene Target p16 CDKN2A Cyclin-dependent kinase 4, Cyclin-dependent kinase 6 p15 CDKN2B Cyclin-dependent kinase 4 p18 CDKN2C Cyclin-dependent kinase

List of genes mutated in cutaneous conditions (108 words) [view diff] exact match in snippet view article find links to article

Hemochromatosis C7orf11 Trichothiodystrophy CBS Cystathionine synthase Homocystinuria CDKN2A Familial melanoma syndrome CHS1 (LYST) Chédiak–Higashi syndrome CXCR4 WHIM

Abemaciclib (1,475 words) [view diff] exact match in snippet view article find links to article

20 July 2023. "Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6". www.clinicaltrials.gov. Retrieved

Methylated-DNA–protein-cysteine methyltransferase (3,871 words) [view diff] exact match in snippet view article find links to article

Seferiadis K, Kolios G (2010). "Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas". World J. Gastroenterol. 16 (28): 3553–60. doi:10

The Cancer Genome Atlas (7,558 words) [view diff] exact match in snippet view article find links to article

heterogeneous, with alterations to CDKN2A, SETD2, TFE3, or increased expression of the NRF2–ARE pathway; loss of expression of CDKN2A and CpG island methylation

IFNA16 (1,035 words) [view diff] exact match in snippet view article find links to article

and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations". Fam. Cancer. 9 (4): 625–33. doi:10.1007/s10689-010-9356-3. PMC 3233727

CDKN2C (1,279 words) [view diff] exact match in snippet view article find links to article

Moretti A, Basso G, Borriello A, Della Ragione F (1998). "Analysis of CDKN2A, CDKN2B, CDKN2C, and cyclin Ds gene status in hepatoblastoma". Hepatology

Astrocytoma (2,182 words) [view diff] exact match in snippet view article find links to article

volume, or increased cerebrospinal fluid volume. Homozygous deletion of CDKN2A/B is the main feature of high grade astrocytoma. In addition, a genome-wide

Auto-sexing (1,160 words) [view diff] exact match in snippet view article find links to article

Leif Andersson (2010). Sex-linked barring in chickens is controlled by the CDKN2A/B tumour suppressor locus. Pigment Cell and Melanoma Research. 23 (4): 521–530

Radiosensitivity (1,456 words) [view diff] exact match in snippet view article find links to article

with radiosensitivity in normal tissues: γH2AX, TP53BP1, VEGFA, CASP3, CDKN2A, IL6, and IL1B. Stochastic effects do not have a threshold of irradiation

Ankyrin repeat (1,393 words) [view diff] exact match in snippet view article find links to article

BAT8; BCL3; BCOR; BCORL1; BTBD11; CAMTA1; CAMTA2; CASKIN1; CASKIN2; CCM1; CDKN2A; CDKN2B; CDKN2C; CDKN2D; CENTB1; CENTB2; CENTB5; CENTG1; CENTG2; CENTG3;

MTAP (2,542 words) [view diff] case mismatch in snippet view article find links to article

"Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line". Cancer Research

Blastic plasmacytoid dendritic cell neoplasm (2,656 words) [view diff] exact match in snippet view article find links to article

the disease: 1) mutations in NRAS, ASXL1, and TP53; 2) deletions of the CDKN2A-ARF-CDKN2B locus on the short arm of chromosome 9, CDKN1B locus on the short

C2C12 (1,181 words) [view diff] exact match in snippet view article find links to article

this in C2C12 skeletal muscle cells is believed to be in the INK4a gene (CDKN2A). Electrical pulse stimulation (EPS) is an in vitro method used to mimic

Mir-584 microRNA precursor family (480 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

Endometrial cancer (10,863 words) [view diff] exact match in snippet view article find links to article

point mutation unknown 17–41% CDH1 loss of heterozygosity unknown 80–90% CDKN2A loss of heterozygosity or epigenetic silencing 20% 40% PIK3CA (oncogene)

Mir-423 microRNA precursor family (565 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

Neurofibroma (3,268 words) [view diff] exact match in snippet view article find links to article

cancers from neurofibromas is associated with the loss of expression of the CDKN2A or TP53 gene in nonmyelinating Schwann cells that also exhibit biallelic

Neoplasm (5,895 words) [view diff] exact match in snippet view article find links to article

Kolios G (July 2010). "Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas". World J. Gastroenterol. 16 (28): 3553–60. doi:10

IFNK (2,561 words) [view diff] exact match in snippet view article find links to article

and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations". Familial Cancer. 9 (4): 625–633. doi:10.1007/s10689-010-9356-3

Dysplastic nevus (1,583 words) [view diff] exact match in snippet view article find links to article

40-50% of cases, the disorder has been linked with germline mutations in the CDKN2A gene, which codes for p16 (a regulator of cell division). Low magnification

Barrett's esophagus (4,555 words) [view diff] exact match in snippet view article find links to article

Maley CC, Sanchez CA, Odze RD, et al. (February 2007). "NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma"

Wound healing assay (1,534 words) [view diff] exact match in snippet view article find links to article

Iwei; Bastian, Boris C.; Judson, Robert L. (July 2018). "Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation". Cancer Cell. 34 (1): 56–68

Mir-32 microRNA precursor family (971 words) [view diff] exact match in snippet view article find links to article

Lindholm PM, Salmenkivi K, Bagwan I, Nicholson AG, Knuutila S (July 2009). "CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant

Gastrointestinal stromal tumor (4,773 words) [view diff] exact match in snippet view article find links to article

potential responsiveness to immunotherapy. The C3 subtype, with frequent CDKN2A aberrations, could benefit from a combination of KIT and CDK4/6 inhibitors

Epigenetics and melanoma (2,896 words) [view diff] exact match in snippet view article find links to article

Glendening, J.M., Flores, J.F., Walker, G.J., et al. 1997. "Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation

Cyclin-dependent kinase 4 (3,573 words) [view diff] exact match in snippet view article find links to article

as well as in its related proteins including D-type cyclins, p16(INK4a), CDKN2A and Rb were all found to be associated with tumorigenesis of a variety of

Virtual karyotype (7,373 words) [view diff] exact match in snippet view article find links to article

(acquired uniparental disomy) has been reported at key loci in ALL, such as CDKN2A gene at 9p, which have prognostic significance. SNP array virtual karyotyping

CDKAL1 (1,118 words) [view diff] exact match in snippet view article find links to article

Kashiwagi A, Kaku K, et al. (March 2008). "Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a

List of Johnson & Johnson products and services (1,877 words) [view diff] exact match in snippet view article find links to article

FiercePharma. 7 December 2020. Retrieved 2021-10-01. "Dual Targeting of CDKN2A and PIK3CA May Offer Better Outcomes in Urothelial Carcinoma". Targeted

Neuroblastoma (7,144 words) [view diff] exact match in snippet view article find links to article

primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene". BMC Genomics. 9: 353. doi:10.1186/1471-2164-9-353. PMC 2527340. PMID 18664255

Amelanotic melanoma (3,231 words) [view diff] exact match in snippet view article find links to article

Linda; Sini, Maria C.; Palmieri, Giuseppe; Scarrà, Giovanna Bianchi (2009). "CDKN2A and MC1R analysis in amelanotic and pigmented melanoma". Melanoma Research

BMI1 (2,644 words) [view diff] exact match in snippet view article find links to article

ER (2008). "BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression". Cancer Res. 68 (16): 6507–15. doi:10.1158/0008-5472.CAN-07-6152

Norman Sharpless (2,088 words) [view diff] exact match in snippet view article find links to article

Kingsmore, D; Stevenson, KS; Koppelstaetter, C; et al. (2013). "Pre-Transplant CDKN2A Expression in Kidney Biopsies Predicts Renal Function and Is a Future Component

Somatic evolution in cancer (9,935 words) [view diff] exact match in snippet view article find links to article

confirmed although mutations in some tumor suppressor genes, including CDKN2A (p16), predispose to clonal expansions that encompass large numbers of crypts

HHIPL1 (1,073 words) [view diff] exact match in snippet view article find links to article

Sato N, Sawabe M, Muramatsu M (2014-01-01). "Associations between the CDKN2A/B, ADTRP and PDGFD polymorphisms and the development of coronary atherosclerosis

ATM serine/threonine kinase (5,695 words) [view diff] exact match in snippet view article find links to article

A, Franco MF, Esteves EB, Scherrer L, Gallo CV, et al. (October 2015). "CDKN2A (p14(ARF)/p16(INK4a)) and ATM promoter methylation in patients with impalpable

Epigenetic priming (2,249 words) [view diff] exact match in snippet view article find links to article

successful. The epigenetic intervention was fruitful in demethylating loci (i.e. CDKN2A, ESR1, HPP1, MGMT, TIMP3) abnormally methylated in gastric carcinomas. A

DNA (cytosine-5)-methyltransferase 3A (3,924 words) [view diff] exact match in snippet view article

Tanzawa H (June 2003). "Over-expression of DNA methyltransferases and CDKN2A gene methylation status in squamous cell carcinoma of the oral cavity".

DNA repair (16,295 words) [view diff] exact match in snippet view article find links to article

K, et al. (July 2010). "Promoter methylation status of hMLH1, MGMT, and CDKN2A/p16 in colorectal adenomas". World Journal of Gastroenterology. 16 (28):

EZH2 (5,395 words) [view diff] exact match in snippet view article find links to article

of EZH2-mediated transcriptional repression include HOXA9, HOXC8, MYT1, CDKN2A and retinoic acid target genes. In cancer, EZH2 may play a role in activation

List of OMIM disorder codes (18,877 words) [view diff] exact match in snippet view article find links to article

neural system tumor syndrome; 155755; CDKN2A Melanoma; 609048; CDK4 Melanoma, cutaneous malignant, 2; 155601; CDKN2A Meleda disease; 248300; SLURP1 Melnick–Needles

Ovarian cancer (21,272 words) [view diff] exact match in snippet view article find links to article

CCND2 upregulation 15% CCNE1 amplification 20% CDK12 high-grade serous CDKN2A downregulation (30%) and deletion (2%) 32% CTNNB1 clear-cell DICER1 missense

Pediatric ependymoma (4,967 words) [view diff] exact match in snippet view article find links to article

homolog of p53, and deletion of the p53 pathway gene p14arf/p16/INK4A (CDKN2A) have also been found in pediatric ependymomas. Over-expression of components

Bhramar Mukherjee (1,227 words) [view diff] exact match in snippet view article find links to article

; DeLancey, J. O.; Raskin, L. (2012). "Risk of Non-Melanoma Cancers in CDKN2A Mutation Carriers". Journal of the National Cancer Institute. 104 (12):

2017 in science (18,534 words) [view diff] exact match in snippet view article find links to article

the University of Rochester Medical Center identify four genes – KRAS, CDKN2A, SMAD4, and TP53 – responsible for how long patients survive with pancreatic

Nutritional epigenetics (8,339 words) [view diff] case mismatch in snippet view article find links to article

(2020-06-01). "Genistein inhibited the proliferation of kidney cancer cells via CDKN2a hypomethylation: role of abnormal apoptosis". International Urology and