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searching for Triple-negative breast cancer 134 found (250 total)

alternate case: triple-negative breast cancer

Mir-361 microRNA precursor family (218 words) [view diff] exact match in snippet view article find links to article

mechanisms. For example, miR-361-5p might act as a suppressor in triple-negative breast cancer (TNBC) by targeting RQCD1 to inhibit the EGFR/PI3K/Akt signaling

MiR-146 (792 words) [view diff] no match in snippet view article find links to article

pathogenesis. mir-146 expression is associated with survival in triple negative breast cancer. miR-146 is thought to be a mediator of inflammation along with

Mir-15 microRNA precursor family (1,206 words) [view diff] no match in snippet view article find links to article

cases. The expression of miR-15a is associated with survival in triple negative breast cancer. miR-15a/16-1 deletion has been shown to accelerate the proliferation

Nobiletin (385 words) [view diff] exact match in snippet view article find links to article

antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer[5]. Nagase H, Yamakuni T, Matsuzaki K, Maruyama Y, Kasahara

SETD3 (gene) (493 words) [view diff] exact match in snippet view article

an inhibition of cytoskeletal function and invasiveness of triple-negative breast cancer cells. Methyltransferase Histone methyltransferase GRCh38: Ensembl

Naoto Ueno (458 words) [view diff] exact match in snippet view article find links to article

which led to novel clinical trials related to inflammatory and triple-negative breast cancer. Ueno moved from Texas to the University of Hawaiʻi to be director

Sherene Loi (918 words) [view diff] exact match in snippet view article find links to article

et al. (2018) Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer. New England Journal of Medicine: 379 (22), 2108-2121 C Sotiriou

PRAME (1,240 words) [view diff] no match in snippet view article find links to article

mediated differentiation and apoptosis. PRAME overexpression in triple negative breast cancer has also been found to promote cancer cell motility through

Myoferlin (711 words) [view diff] exact match in snippet view article find links to article

overexpressed in several types of cancers, especially pancreas and triple-negative breast cancer. Overexpression of myoferlin is associated with proliferation

FANCM (1,914 words) [view diff] no match in snippet view article find links to article

is also associated with a higher than average frequency of triple negative breast cancer in heterozygous carriers. FANCM carriers also have elevated

Immunomedics (409 words) [view diff] exact match in snippet view article find links to article

the FDA for the treatment of adult patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for patients

Bhuvaneswari Ramaswamy (632 words) [view diff] exact match in snippet view article find links to article

grant to study the link between breastfeeding and risk for triple-negative breast cancer. As the principal investigator, Ramaswamy and her research team

CAD protein (1,164 words) [view diff] no match in snippet view article find links to article

has been shown to be specifically helpful in the treatment of Triple Negative Breast Cancer (TNBC) in vitro and in vivo. GRCh38: Ensembl release 89: ENSG00000084774

Antibody–drug conjugate (4,234 words) [view diff] no match in snippet view article find links to article

2019. Retrieved 3 January 2020. "FDA Approves New Therapy for Triple Negative Breast Cancer That Has Spread, Not Responded to Other Treatments". FDA. 22

Proteoglycan (835 words) [view diff] exact match in snippet view article find links to article

PMID 28270211. Ibrahim, Sherif (2013). "Syndecan-1 (CD138) modulates triple-negative breast cancer stem cell properties via regulation of LRP-6 and IL-6-mediated

Liza Makowski Hayes (794 words) [view diff] no match in snippet view article find links to article

impacts the immune system and response to immunotherapy for triple negative breast cancer. Her research was also supported by a $100,000 grant from The

Richard Pestell (2,730 words) [view diff] exact match in snippet view article find links to article

immunologically “cold” tumors to “hot” ones, in the context of metastatic triple-negative breast cancer and checkpoint inhibitor responsiveness. Under Pestell’s leadership

KH-3 (drug) (416 words) [view diff] exact match in snippet view article

"Functional inhibition of the RNA-binding protein HuR sensitizes triple-negative breast cancer to chemotherapy". Molecular Oncology. 17 (10): 1962–1980. doi:10

Suberoyl chloride (92 words) [view diff] no match in snippet view article find links to article

hybrid compounds that have antiproliferative activity against triple negative breast cancer cells. It is also used as a cross-linking agent to cross-link

MAP kinase kinase kinase (1,423 words) [view diff] no match in snippet view article find links to article

factor receptor (EGFR) can lead to tumor formation, such as triple negative breast cancer. A mutation in the JNK or p38 family of MAPK or their MAPKKK

Anthracycline (5,069 words) [view diff] no match in snippet view article find links to article

receptors that can be targeted. Compared to non-triple negative breast cancer patients, triple negative breast cancer patients have shown better response rate

CTP synthase 1 (3,095 words) [view diff] exact match in snippet view article find links to article

et al. (January 2022). "CTPS1 promotes malignant progression of triple-negative breast cancer with transcriptional activation by YBX1". Journal of Translational

Fast track (FDA) (829 words) [view diff] case mismatch in snippet view article

Designation by FDA for Sacituzumab Govitecan (IMMU-132) for Triple-Negative Breast Cancer Therapy". GlobeNewswire News Room (Press release). 5 January

Ipatasertib (143 words) [view diff] no match in snippet view article find links to article

as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer" at ClinicalTrials.gov Lin J, Sampath D, Nannini MA, Lee BB

Crystal C. Watkins Johansson (2,182 words) [view diff] case mismatch in snippet view article find links to article

Coping Among African American Women With Breast Cancer and Triple-Negative Breast Cancer. Oncol Nurs Forum. 2017;44(6):689‐702. doi:10.1188/17.ONF.689-702

Vincent Cryns (505 words) [view diff] case mismatch in snippet view article find links to article

"Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression". Clinical Cancer

Abedelnasser Abulrob (543 words) [view diff] no match in snippet view article find links to article

"Novel lyp 1 targeted iron oxide nanoparticle early detection triple negative breast cancer". Advances in Engineering. Archived from the original on 2021-01-30

CPNE1 (1,819 words) [view diff] exact match in snippet view article find links to article

causing an implication in the regulation of the pathway.) In triple-negative breast cancer, CPNE1 increases tumorigenesis and radioresistance, due to the

Owkin (2,099 words) [view diff] exact match in snippet view article find links to article

predicting histological response to neoadjuvant chemotherapy in triple-negative breast cancer" Nat Med (2023). 10.1038/s41591-022-02155 Saiilard et al., “Pacpaint:

Nutriepigenomics (6,367 words) [view diff] no match in snippet view article find links to article

natural combattant to the rare phenotype of triple negative breast cancer. Triple negative breast cancer is a form of cancer that quickly mutates and

Helen Piwnica-Worms (586 words) [view diff] exact match in snippet view article find links to article

In 2019, Piwnica-Worms and her research team discovered that triple-negative breast cancer cells could develop resistance to frontline, or neoadjuvant

Alliance for Clinical Trials in Oncology (290 words) [view diff] case mismatch in snippet view article find links to article

completed in 2014. Demystifying Immunotherapy for Early-Stage Triple-Negative Breast Cancer Suh, Kangho; Veena Shankaran, M. D.; Bansal, Aasthaa (10 May

MK-2870 (293 words) [view diff] no match in snippet view article find links to article

Efficacy and safety of SKB264 for previously treated metastatic triple negative breast cancer in Phase 2 study". Cancer Research. 83 (5_Supplement): OT1–03–02-OT1-03-02

MAGEA10 (424 words) [view diff] exact match in snippet view article find links to article

(2012). "High expression of MAGE-A10 cancer-testis antigen in triple-negative breast cancer". Med. Oncol. 29 (3): 1586–91. doi:10.1007/s12032-011-0120-9

Selisistat (237 words) [view diff] exact match in snippet view article find links to article

SIRT1 inhibitor, enhances paclitaxel activity in luminal and triple-negative breast cancer: in silico, in vitro, and in vivo studies". Journal of Enzyme

Sutton Grammar School (4,792 words) [view diff] no match in snippet view article find links to article

press coverage in 2016 after he discovered a way to make deadly triple negative breast cancer more treatable. He conducted this research in the school's laboratories

PELP-1 (3,924 words) [view diff] no match in snippet view article find links to article

in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells". Breast Cancer Research and Treatment. 150 (3): 487–99

Cediranib (647 words) [view diff] case mismatch in snippet view article find links to article

Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer" at ClinicalTrials.gov Liu JF, Barry WT, Birrer M, Lee JM, Buckanovich

Triplatin tetranitrate (528 words) [view diff] exact match in snippet view article find links to article

glycosaminoglycan status for precision medicine of platinums in triple-negative breast cancer". Mol. Cancer Ther. 21: 271–281. doi:10.1158/1535-7163.MCT-20-0969

Padnarsertib (321 words) [view diff] no match in snippet view article find links to article

Inhibitor of PAK4 and NAMPT, Leads to Downregulation of mTORC2 in Triple Negative Breast Cancer Cells". Chemical Research in Toxicology. 33 (2): 482–491. doi:10

Tinengotinib (129 words) [view diff] case mismatch in snippet view article find links to article

Spectrum-Selective Small-Molecule Kinase Inhibitor, Is Highly Active Against Triple-Negative Breast Cancer". Molecular Cancer Therapeutics. 22 (2): 205–214. doi:10.1158/1535-7163

USP1 (686 words) [view diff] exact match in snippet view article find links to article

"UCHL1 contributes to insensitivity to endocrine therapy in triple-negative breast cancer by deubiquitinating and stabilizing KLF5". Breast Cancer Research

MIRN21 (2,697 words) [view diff] no match in snippet view article find links to article

diagnosis. miR-21 expression was associated with survival in 53 triple negative breast cancer patients. miR-21 can also be detected in human faeces from colorectal

Katherine A. Hoadley (788 words) [view diff] exact match in snippet view article find links to article

2010. Retrieved December 11, 2020. "Combination therapy for triple-negative breast cancer disappointing". unclineberger.org. June 12, 2012. Retrieved

Proliferative index (1,559 words) [view diff] no match in snippet view article find links to article

grade index to predict response to neoadjuvant chemotherapy in triple negative breast cancer". European Journal of Nuclear Medicine and Molecular Imaging

MiR-27 (1,108 words) [view diff] no match in snippet view article find links to article

cancer cells. mir-27b expression is associated with survival in triple negative breast cancer patients. Inhibition of miR-27 by antisense molecules decreases

Nanophotonics (2,713 words) [view diff] exact match in snippet view article find links to article

like adriamycin from nanoporous optical antennas to target triple-negative breast cancer and mitigate exocytosis anti-cancer drug resistance mechanisms

Kate Figes (999 words) [view diff] no match in snippet view article find links to article

of the decision". Figes was diagnosed in September 2016 with triple negative breast cancer, which had metastasised. She wrote about her terminal illness

MDA-MB-453 (1,331 words) [view diff] no match in snippet view article find links to article

characteristics, the MDA-MB-453 cell cancer line is now classified as a Triple Negative Breast Cancer cell line model. One study suggests that the MDA-MB-453 cell

Rana P Singh (1,620 words) [view diff] exact match in snippet view article find links to article

oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer". British Journal of Cancer. 124 (3): 604–615. doi:10.1038/s41416-020-01137-4

GJB2 (1,179 words) [view diff] exact match in snippet view article find links to article

Rao V, et al. (February 2018). "Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase". Nature

Fayaz A. Malik (1,634 words) [view diff] no match in snippet view article find links to article

regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model". Oncogene. 34 (6): 671–680. doi:10.1038/onc.2014.4. PMC 4285772

Early Mitotic Inhibitor 1 (2,170 words) [view diff] exact match in snippet view article find links to article

cancer cells to PARP inhibitor olaparib which is used to treat triple-negative breast cancer and thus, ensuring a sustained EMI1 expression is critical for

Ironomycin (607 words) [view diff] no match in snippet view article find links to article

of drug resistance cancers such as acute myeloid leukemia, triple negative breast cancer, pancreatic cancer and non-hodgkin lymphoma. A team from ICSN

Enzalutamide (4,747 words) [view diff] exact match in snippet view article find links to article

enzalutamide, an androgen receptor (AR) inhibitor, in advanced AR+ triple-negative breast cancer (TNBC)". Cancer Research. 75 (9 Supplement): P5-19-09. doi:10

LOXL2 (1,207 words) [view diff] exact match in snippet view article find links to article

"LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells". Oncogene. 39 (1): 79–121. doi:10.1038/s41388-019-0969-1

Eric Winer (985 words) [view diff] case mismatch in snippet view article find links to article

Cyclophosphamide on Pathologic Complete Response Rates in Stage II to III Triple-Negative Breast Cancer: CALGB 40603 (Alliance). Journal of Clinical Oncology. 2015;33:13-21

CNOT9 (620 words) [view diff] exact match in snippet view article find links to article

J, Zhou X (February 2019). "Overexpression of miR-361-5p in triple-negative breast cancer (TNBC) inhibits migration and invasion by targeting RQCD1 and

Sabizabulin (787 words) [view diff] case mismatch in snippet view article find links to article

"An Orally Available Tubulin Inhibitor, VERU-111, Suppresses Triple-Negative Breast Cancer Tumor Growth and Metastasis and Bypasses Taxane Resistance"

CMLD-2 (440 words) [view diff] exact match in snippet view article find links to article

Marimuthu S, Shah A, et al. (March 2023). "MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR"

Breast cancer (15,696 words) [view diff] exact match in snippet view article find links to article

31% survive at least five years from the time of diagnosis. Triple-negative breast cancer (up to 15% of cases) and inflammatory breast cancer (up to 5%

Sofia Merajver (881 words) [view diff] case mismatch in snippet view article find links to article

drug research and developed a dual inhibitor technology for Triple-Negative Breast Cancer which alters the cellular localization of c-Strc/p38 kinase

CIP2A (1,824 words) [view diff] no match in snippet view article find links to article

KF (April 2012). "CIP2A is a target of bortezomib in human triple negative breast cancer cells". Breast Cancer Research. 14 (2): R68. doi:10.1186/bcr3175

Targeted intra-operative radiotherapy (2,802 words) [view diff] exact match in snippet view article find links to article

value of adjuvant radiotherapy on survival and recurrence in triple-negative breast cancer: A systematic review and meta-analysis of 5507 patients". Cancer

MTDH (1,727 words) [view diff] no match in snippet view article find links to article

(March 2020). "A novel metadherinΔ7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NFĸB-SIRT3

OBI Pharma, Inc. (975 words) [view diff] exact match in snippet view article find links to article

III trial of Adagloxad Simolenin (OBI-822) and OBI-821 for triple-negative breast cancer completed its first interim analysis, with the Data and Safety

C16orf78 (1,205 words) [view diff] case mismatch in snippet view article find links to article

Anthony; Das, Gokul M. (3 October 2014). "Highly Adaptable Triple-Negative Breast Cancer Cells as a Functional Model for Testing Anticancer Agents".

DarwinHealth (981 words) [view diff] exact match in snippet view article find links to article

Piwnica-Worms, Helen (2019). "Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state". Science Translational

Famitinib (548 words) [view diff] case mismatch in snippet view article find links to article

Camrelizumab and Nab-Paclitaxel for Advanced Immunomodulatory Triple-Negative Breast Cancer (FUTURE-C-Plus): An Open-Label, Single-Arm, Phase II Trial"

Basal-like carcinoma (1,745 words) [view diff] exact match in snippet view article find links to article

Robertson JF, Ellis IO (January 2007). "Prognostic markers in triple-negative breast cancer". Cancer. 109 (1): 25–32. doi:10.1002/cncr.22381. PMID 17146782

Cytokine-induced killer cell (2,335 words) [view diff] no match in snippet view article find links to article

the efficacy of a combined approach (CIK + Cetuximab) against triple negative breast cancer (TNBC), an aggressive tumor that still requires therapeutic

Basal-like carcinoma (1,745 words) [view diff] exact match in snippet view article find links to article

Robertson JF, Ellis IO (January 2007). "Prognostic markers in triple-negative breast cancer". Cancer. 109 (1): 25–32. doi:10.1002/cncr.22381. PMID 17146782

Checkpoint inhibitor (2,406 words) [view diff] exact match in snippet view article find links to article

Schmidt M (January 2019). "Atezolizumab for the treatment of triple-negative breast cancer". Expert Opinion on Investigational Drugs. 28 (1): 1–5. doi:10

Nucleolar and spindle associated protein 1 (577 words) [view diff] case mismatch in snippet view article find links to article

Reduced Levels of BRCA1 Expression Predict Poor Prognosis in Triple-Negative Breast Cancer". PLOS ONE. 10 (10) e0140572. Bibcode:2015PLoSO..1040572C. doi:10

BRCA2 (7,957 words) [view diff] exact match in snippet view article find links to article

by mutant p53 accumulation and loss of BRCA1/2 proteins in triple-negative breast cancer, adversely affects survival". Histopathology. 68 (5): 702–12

Jason S. Lewis (932 words) [view diff] case mismatch in snippet view article find links to article

Targeting Compared with 18F-FDG PET in MYC-Overexpressing Human Triple-Negative Breast Cancer". Journal of Nuclear Medicine. 59 (1): 51–57. doi:10.2967/jnumed

Lewis C. Cantley (3,294 words) [view diff] exact match in snippet view article find links to article

women's cancers, and he now leads a national effort targeting triple-negative breast cancer and ovarian cancer with novel drug combinations. Recent research

Breast cancer stem cell (1,618 words) [view diff] no match in snippet view article find links to article

S2CID 207638818. Anders, C; Carey, LA (2008). "Understanding and treating triple negative breast cancer". Oncology. 22 (11): 1233–1239. PMC 2868264. PMID 18980022.

USERN (1,740 words) [view diff] no match in snippet view article find links to article

Survivin targeted siRNA using cancer selective nanoparticles for triple negative breast cancer therapy Hao Chen (China) in Medical Sciences For: A tunable

AXL receptor tyrosine kinase (2,446 words) [view diff] exact match in snippet view article find links to article

with poor survival in numerous aggressive tumors including triple-negative breast cancer (TNBC), acute myeloid leukemia (AML), non-small-cell lung cancer

Randy Blythe (4,664 words) [view diff] no match in snippet view article find links to article

go to Blythe’s sister-in-law Bianca, who is battling Stage 3 triple negative breast cancer. In 2019 Blythe auctioned off his gold album plaque for Lamb

Genetic counseling (11,408 words) [view diff] no match in snippet view article find links to article

high likelihood to be hereditary (e.g. male breast cancer, triple negative breast cancer, ovarian cancer, metastatic or high-grade prostate cancer, pancreatic

C20orf144 (743 words) [view diff] exact match in snippet view article find links to article

"Microarray-based SNP genotyping to identify genetic risk factors of triple-negative breast cancer (TNBC) in South Indian population". Molecular and Cellular Biochemistry

CTAG1B (2,389 words) [view diff] no match in snippet view article find links to article

"NY-ESO-1 cancer testis antigen demonstrates high immunogenicity in triple negative breast cancer". PLOS ONE. 7 (6) e38783. Bibcode:2012PLoSO...738783A. doi:10

TMEM171 (1,638 words) [view diff] exact match in snippet view article find links to article

expression of TMEM171 is a favorable prognostic marker. In triple-negative breast cancer cells, immuno-activation by tumor necrosis factor alpha (TNFα)

CCL5 (2,508 words) [view diff] exact match in snippet view article find links to article

(July 2013). "CCL5 as a potential immunotherapeutic target in triple-negative breast cancer". Cellular & Molecular Immunology. 10 (4): 303–310. doi:10.1038/cmi

Mir-181 microRNA precursor (4,189 words) [view diff] no match in snippet view article find links to article

system. miR-181a expression is associated with survival in triple negative breast cancer. Patients with low expression have lower probability of survival

C-C chemokine receptor type 7 (2,841 words) [view diff] no match in snippet view article find links to article

cancer. In human breast cancer patients, expression of CCR7 in triple negative breast cancer increases the length of disease free survival following surgical

L. S. Shashidhara (2,604 words) [view diff] case mismatch in snippet view article find links to article

Kulkarni, Madhura (November 2020). "Meta-Analysis of Prevalence of Triple-Negative Breast Cancer and Its Clinical Features at Incidence in Indian Patients With

TACSTD2 (1,362 words) [view diff] case mismatch in snippet view article find links to article

Designation by FDA for Sacituzumab Govitecan (IMMU-132) for Triple-Negative Breast Cancer Therapy [1] Linnenbach AJ, Seng BA, Wu S, Robbins S, Scollon

ACSL4 (2,015 words) [view diff] no match in snippet view article find links to article

ACSL4 also is positively correlated with a unique subtype of triple negative breast cancer (TNBC), which is characterized by the absence of androgen receptor

Zinc transporter SLC39A7 (1,968 words) [view diff] exact match in snippet view article find links to article

polyclonal antibodies specifically targeting ZIP7 to both human triple-negative breast cancer cells (TNBC) and normal breast epithelial cells (NBE) obtained

Cancer in Ghana (1,676 words) [view diff] case mismatch in snippet view article find links to article

Solomon; et al. (2010). "African Ancestry and Higher Prevalence of Triple-Negative Breast Cancer: Findings from an international study". Cancer. 116 (21): 4926–4932

FAM227B (1,705 words) [view diff] exact match in snippet view article find links to article

"LOXL2-mediated H3K4 oxidation reduces chromatin accessibility in triple-negative breast cancer cells". Oncogene. 39 (1): 79–121. doi:10.1038/s41388-019-0969-1

Genetic heterogeneity (3,992 words) [view diff] no match in snippet view article find links to article

(2018-09-06). "A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging". Cell. 174 (6): 1373–1387

FAM43A (1,659 words) [view diff] no match in snippet view article find links to article

precursor (ETP) acute lymphoblastic leukemia (ALL) (GDS4299) and triple negative breast cancer (TNBC) cell lines Hs578T (GDS4092). FAM43A expression map of

ERCC4 (3,318 words) [view diff] no match in snippet view article find links to article

JJ (2014). "Combined genetic and nutritional risk models of triple negative breast cancer". Nutr Cancer. 66 (6): 955–63. doi:10.1080/01635581.2014.932397

CIB1 (2,206 words) [view diff] exact match in snippet view article find links to article

"CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer". Breast Cancer Research and Treatment. 152 (2): 337–346. doi:10

Healthcare in Ghana (3,979 words) [view diff] case mismatch in snippet view article find links to article

Solomon; et al. (2010). "African Ancestry and Higher Prevalence of Triple-Negative Breast Cancer: Findings from an international study". Cancer. 116 (21): 4926–4932

MiR-155 (5,688 words) [view diff] no match in snippet view article find links to article

analysis that miR-155 expression is associated with survival in triple negative breast cancer. MicroRNA GRCh38: Ensembl release 89: ENSG00000283904 – Ensembl

Transfer RNA (8,279 words) [view diff] case mismatch in snippet view article find links to article

Contribution of miRNA Isoforms and tRNA-Derived Fragments to Triple-Negative Breast Cancer". Cancer Res. 78 (5): 1140–54. doi:10.1158/0008-5472.CAN-17-1947

Sonodynamic therapy (9,372 words) [view diff] exact match in snippet view article find links to article

sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer". Biomaterials. 269 120639. doi:10.1016/j.biomaterials.2020

Metastatic breast cancer (5,262 words) [view diff] no match in snippet view article find links to article

platinum-based regimens. However, in women with metastatic triple negative breast cancer, there may be a moderate survival benefit from platinum-based

GDF11 (3,985 words) [view diff] exact match in snippet view article find links to article

al. (23) identified a tumor-suppressive role of GDF11 in a triple-negative breast cancer (TNBC). GRCh38: Ensembl release 89: ENSG00000135414 – Ensembl

Cancer in adolescents and young adults (3,097 words) [view diff] exact match in snippet view article find links to article

tumors, larger primary tumors, and a greater propensity for triple-negative breast cancer. Adolescents and young adults with breast cancer generally have

Mauro Ferrari (2,881 words) [view diff] no match in snippet view article find links to article

PMC 4066479. PMID 24876273. Chen X, et al. (2014). "XBP1 promotes triple negative breast cancer by controlling the HIF1α pathway". Nature. 508 (7494): 103–107

Wafik El-Deiry (3,677 words) [view diff] no match in snippet view article find links to article

receptors. Unlike TRAIL which is active against a subset of triple negative breast cancer (TNBC), ONC201 has preclinical anti-tumor efficacy against ER/PR+

Ellinor Peerschke (1,953 words) [view diff] no match in snippet view article find links to article

Tumor Growth in an Orthotopic Murine Xenotransplant Model of Triple Negative Breast Cancer". Antibodies. 9 (4): 51. doi:10.3390/antib9040051. PMC 7709104

GPER (4,000 words) [view diff] exact match in snippet view article find links to article

et al. (May 2014). "GPER functions as a tumor suppressor in triple-negative breast cancer cells". Journal of Cancer Research and Clinical Oncology. 140

T-box transcription factor T (4,186 words) [view diff] exact match in snippet view article find links to article

(October 2016). "Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer". Endocrine-Related Cancer. 23 (10): 783–796. doi:10.1530/ERC-16-0037

TEAD1 (4,032 words) [view diff] exact match in snippet view article find links to article

copy number alterations and expression of relevant genes in triple-negative breast cancer". Genes, Chromosomes & Cancer. 47 (6): 490–9. doi:10.1002/gcc

CCR5 receptor antagonist (5,550 words) [view diff] exact match in snippet view article find links to article

allowed to initiate a Phase Ib/II clinical trial for metastatic triple-negative breast cancer (mTNBC) patients. On February 20, 2019, CytoDyn announced that

Alvin J. Siteman Cancer Center (5,236 words) [view diff] exact match in snippet view article find links to article

small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent

Gene expression (10,154 words) [view diff] case mismatch in snippet view article find links to article

Elements Identifies Pathologically Relevant Signaling Pathways in Triple-Negative Breast Cancer". iScience. 23 (6) 101249. Bibcode:2020iSci...23j1249N. doi:10

Datopotamab deruxtecan (1,437 words) [view diff] exact match in snippet view article find links to article

et al. (2023). "Safety evaluation of Datopotamab deruxtecan for triple-negative breast cancer: a meta-analysis". Cancer Treatment and Research Communications

Transient receptor potential channel (5,866 words) [view diff] no match in snippet view article find links to article

and TRPV2 is a potential biomarker and therapeutic target in triple negative breast cancer. In addition to TLR4 mediated pathways, certain members of the

Beta blocker (8,976 words) [view diff] exact match in snippet view article find links to article

(June 2016). "Inhibition of β2-adrenergic receptor reduces triple-negative breast cancer brain metastases: The potential benefit of perioperative β-blockade"

Natural killer cell (9,220 words) [view diff] exact match in snippet view article find links to article

critical role in promoting drug-induced cell death in human triple-negative breast cancer. Since NK cells recognize target cells when they express nonself

Bicalutamide (21,795 words) [view diff] exact match in snippet view article find links to article

"Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells". Endocrine-Related Cancer. 23 (4): 323–34. doi:10.1530/ERC-16-0068

Epigenetics (18,275 words) [view diff] exact match in snippet view article find links to article

"Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis". Proceedings of the National

20-Hydroxyeicosatetraenoic acid (8,906 words) [view diff] no match in snippet view article find links to article

synthesis, decreases pro-angiogenic factors and inhibits growth of triple negative breast cancer in mice". PLOS ONE. 9 (12) e116247. Bibcode:2014PLoSO...9k6247B

Paul Billings (3,802 words) [view diff] case mismatch in snippet view article find links to article

a Tumor-Informed Circulating Tumor DNA Test in an Advanced Triple-Negative Breast Cancer Patient: A Case Report. Case Rep Oncol. 2022;15(2):473–479.

RNA-targeting small molecule drugs (4,480 words) [view diff] no match in snippet view article find links to article

mice, inhibiting tumor growth in a xenograft mouse model of triple negative breast cancer upon i.p. injection. RNA-targeting small molecule drug discovery

GTx-027 (718 words) [view diff] exact match in snippet view article find links to article

"Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling". PLOS

Amitriptyline (9,292 words) [view diff] exact match in snippet view article find links to article

PARP1 inhibitor (OL-1) with apoptosis-inducing mechanisms in triple-negative breast cancer". Scientific Reports. 6 (1) 3: 3. doi:10.1038/s41598-016-0007-2

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A.C. ... & Jeffrey S.S. 2014. Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to

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preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative

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Wang LL, et al. (30 April 2021). "Resibufogenin Suppresses Triple-Negative Breast Cancer Angiogenesis by Blocking VEGFR2-Mediated Signaling Pathway"

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(September 2015). "CDK7-dependent transcriptional addiction in triple-negative breast cancer". Cell. 163 (1): 174–86. doi:10.1016/j.cell.2015.08.063. PMC 4583659

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"Selective androgen receptor modulators (SARMs) negatively regulate triple-negative breast cancer growth and epithelial:mesenchymal stem cell signaling". PLOS

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10-year anniversary. Although Angelica's diagnosis of stage 2 triple-negative breast cancer last year was a difficult journey, the couple is now celebrating

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on resistant cell lines; TKT inhibition reduces cell growth. Triple-negative breast cancer (TNBC): Combined with chemotherapeutic agents (e.g. doxorubicin

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Molecular Features of Luminal Androgen Receptor Subtype in Triple Negative Breast Cancer Cells". secondary. J Breast Cancer. 26 (1): 60–76. doi:10.4048/jbc