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searching for Steatohepatitis 135 found (175 total)

Alcoholic liver disease (2,879 words) [view diff] no match in snippet view article find links to article

Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption

Obeticholic acid (1,997 words) [view diff] exact match in snippet view article find links to article

disease progression, liver transplantation or death. Non-alcoholic steatohepatitis is a common cause of abnormal liver function with histological features

Intercept Pharmaceuticals (886 words) [view diff] exact match in snippet view article find links to article

biliary cholangitis, non-alcoholic fatty liver disease (or non-alcoholic steatohepatitis, NASH), cirrhosis, portal hypertension, primary sclerosing cholangitis

Cenicriviroc (560 words) [view diff] exact match in snippet view article find links to article

HIV infection and in combination with Tropifexor for non-alcoholic steatohepatitis. It is being developed by Takeda and Tobira Therapeutics.[citation

Semaglutide (7,521 words) [view diff] exact match in snippet view article find links to article

weight loss, and the treatment of metabolic-associated steatohepatitis (nonalcoholic steatohepatitis). Semaglutide is a glucagon-like peptide-1 receptor

Apararenone (144 words) [view diff] exact match in snippet view article find links to article

Pharma for the treatment of diabetic nephropathies and non-alcoholic steatohepatitis. It was also previously being developed for the treatment of hypertension

Cilofexor (370 words) [view diff] exact match in snippet view article find links to article

treatment of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and primary sclerosing cholangitis (PSC). It is being investigated

Nidufexor (126 words) [view diff] exact match in snippet view article find links to article

trials for the treatment of diabetic nephropathy and nonalcoholic steatohepatitis. GSK-4112 SR9009 SR9011 Chianelli D, Rucker PV, Roland J, Tully DC

AST/ALT ratio (979 words) [view diff] exact match in snippet view article find links to article

elevated in a liver disease pattern in patients with nonalcoholic steatohepatitis, and it is frequently elevated in an alcoholic liver disease pattern

Remogliflozin etabonate (710 words) [view diff] exact match in snippet view article find links to article

is a drug of the gliflozin class for the treatment of non-alcoholic steatohepatitis ("NASH") and type 2 diabetes. Remogliflozin was discovered by the Japanese

Tropifexor (259 words) [view diff] exact match in snippet view article find links to article

developed for the treatment of cholestatic liver diseases and nonalcoholic steatohepatitis (NASH). In combination with cenicriviroc, a CCR2 and CCR5 receptor

Focal fatty liver (123 words) [view diff] exact match in snippet view article find links to article

liver. It is likely to have different pathogenesis than non-alcoholic steatohepatitis which is a diffuse process. FFL may result from altered venous flow

Kupffer cell (2,352 words) [view diff] exact match in snippet view article find links to article

alcoholic liver disease, viral hepatitis, intrahepatic cholestasis, steatohepatitis, activation or rejection of the liver during liver transplantation

Cirrhosis (12,482 words) [view diff] exact match in snippet view article find links to article

including alcohol-related liver disease, metabolic dysfunction–associated steatohepatitis (MASH – the progressive form of metabolic dysfunction–associated steatotic

Testosterone undecanoate (3,697 words) [view diff] exact match in snippet view article find links to article

intramuscular testosterone undecanoate for the treatment of non-alcoholic steatohepatitis (NASH) was initiated in the United Kingdom. In the United States in

Thiazolidinedione (2,172 words) [view diff] exact match in snippet view article find links to article

out since 2005 in polycystic ovary syndrome (PCOS), non-alcoholic steatohepatitis (NASH), psoriasis, autism, ovarian hyperstimulation syndrome (by VEGF

Rev-Erb (959 words) [view diff] exact match in snippet view article find links to article

family name. The receptors are potential drug targets for non-alcoholic steatohepatitis. Key functions of REV-ERB alpha and REV-ERB beta circadian proteins

Metabolic dysfunction–associated steatotic liver disease (15,500 words) [view diff] exact match in snippet view article find links to article

fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH, now known as metabolic dysfunction associated steatohepatitis (MASH)) have been used to describe

Emricasan (473 words) [view diff] exact match in snippet view article find links to article

fast track designation by the FDA for the treatment of non-alcoholic steatohepatitis cirrhosis The substance is the first pan-caspase inhibitor to advance

TOR1AIP1 (813 words) [view diff] exact match in snippet view article find links to article

secretion and causes non-alcoholic fatty liver disease and non-alcoholic steatohepatitis GRCh38: Ensembl release 89: ENSG00000143337 – Ensembl, May 2017 GRCm38:

Schrödinger, Inc. (809 words) [view diff] exact match in snippet view article find links to article

inhibitor was moving through late-stage clinical trials in non-alcoholic steatohepatitis. In November 2013, Schrödinger, in collaboration with Cycle Computing

Efruxifermin (459 words) [view diff] exact match in snippet view article find links to article

treat metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), and type 2 diabetes. Efruxifermin

Volixibat (244 words) [view diff] exact match in snippet view article find links to article

medication under development as a possible treatment for nonalcoholic steatohepatitis (NASH), the most severe form of non-alcoholic fatty liver disease (NAFLD)

Clesacostat (1,469 words) [view diff] exact match in snippet view article find links to article

treatment of metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), with liver fibrosis. It is a liver-targeted

HEC88473 (135 words) [view diff] exact match in snippet view article find links to article

developed by the Chinese company HEC Pharm for diabetes and non-alcoholic steatohepatitis. Pan, Qi; Lin, Shushan; Li, Yu; Liu, Liang; Li, Xiaoping; Gao, Xianglei;

Pegozafermin (312 words) [view diff] exact match in snippet view article find links to article

glycopegylated FGF21 analog developed for the treatment of nonalcoholic steatohepatitis and hypertriglyceridemia. Loomba, Rohit; Sanyal, Arun J.; Kowdley,

Ervogastat (173 words) [view diff] exact match in snippet view article find links to article

O-acyltransferase 2 inhibitor developed by Pfizer for non-alcoholic steatohepatitis. Its development was previously halted by the company but resumed in

Belapectin (233 words) [view diff] exact match in snippet view article find links to article

developed by Galectin Therapeutics for the treatment of non-alcoholic steatohepatitis. In a phase 2b/3 trial belapectin at 2 mg/kg/LBW reduces varices development

HEC96719 (182 words) [view diff] exact match in snippet view article find links to article

tricyclic farnesoid X receptor agonist developed for non-alcoholic steatohepatitis. Cao, Shengtian; Yang, Xinye; Zhang, Zheng; Wu, Junwen; Chi, Bo; Chen

Resmetirom (761 words) [view diff] exact match in snippet view article find links to article

noncirrhotic metabolic dysfunction associated steatohepatitis (MASH) (formerly known as nonalcoholic steatohepatitis NASH). It is structurally similar to the

Elafibranor (996 words) [view diff] exact match in snippet view article find links to article

type 2 diabetes, dyslipidemia, and metabolic dysfunction–associated steatohepatitis. "Iqirvo (Ipsen Pty Ltd)". Therapeutic Goods Administration (TGA).

Omesdafexor (159 words) [view diff] exact match in snippet view article find links to article

small-molecule farnesoid X receptor (FXR) agonist developed for nonalcoholic steatohepatitis and colitis. Harrison, S. A.; Bashir, M. R.; Lee, K. J.; Shim-Lopez

VK2809 (243 words) [view diff] exact match in snippet view article find links to article

Therapeutics in a phase II trial for the treatment of nonalcoholic steatohepatitis and is also being investigated for glycogen storage disease type Ia

HU6 (403 words) [view diff] exact match in snippet view article find links to article

fat in humans with risk factors for metabolic dysfunction-associated steatohepatitis. In a phase 2a trial, the higher dosage levels reduced liver fat on

Efocipegtrutide (200 words) [view diff] exact match in snippet view article find links to article

peptide 1 receptors. It is being studied for obesity and nonalcoholic steatohepatitis. Kalra, Sanjay; Bhattacharya, Saptarshi; Kapoor, Nitin (August 2021)

Metreleptin (1,092 words) [view diff] exact match in snippet view article find links to article

In a clinical study, metreleptin treatment improved non-alcoholic steatohepatitis (fatty liver disease) both in patients with partial lipodystrophy and

Melissa Palmer (999 words) [view diff] exact match in snippet view article find links to article

where she was in charge of the global development of Non-alcoholic steatohepatitis (NASH) and other liver disease programs. Prior to joining the pharmaceutical

Hepatocellular carcinoma (10,359 words) [view diff] exact match in snippet view article find links to article

include hepatitis infection such as (hepatitis B, C or D), non-alcoholic steatohepatitis (NASH), alcoholic liver disease, or exposure to toxins such as aflatoxin

Aldafermin (370 words) [view diff] exact match in snippet view article find links to article

fibroblast growth factor 19 (FGF19) analogue developed for non-alcoholic steatohepatitis. Babu, A.F.; Iannone, V.; Lok, J.; Gomez-Gallego, C.; D'Auria, G.;

ZED1227 (168 words) [view diff] exact match in snippet view article find links to article

inhibitor developed by Zedira GmbH for celiac disease and nonalcoholic steatohepatitis. Schuppan, Detlef; Mäki, Markku; Lundin, Knut E.A.; Isola, Jorma; Friesing-Sosnik

Rencofilstat (232 words) [view diff] exact match in snippet view article find links to article

inhibitor and analog of cyclosporine A developed for nonalcoholic steatohepatitis and hepatocellular carcinoma. Harrison, Stephen A.; Mayo, Patrick R

Primary biliary cholangitis (6,163 words) [view diff] exact match in snippet view article find links to article

are absent, or when co-existent autoimmune hepatitis or nonalcoholic steatohepatitis is suspected. Liver biopsy can be useful to stage the disease for fibrosis

Interleukin 19 (1,943 words) [view diff] exact match in snippet view article find links to article

is an essential regulator of neutrophil development. Nonalcoholic steatohepatitis (NASH) is a disease that has progressed from nonalcoholic fatty liver

Licogliflozin (183 words) [view diff] exact match in snippet view article find links to article

as treating symptoms of polycystic ovary syndrome and nonalcoholic steatohepatitis. Zaki AM, Abo-Elnour DE, Abdalla YE, Hassan RY, Salama MK, Elboraay

Denifanstat (313 words) [view diff] exact match in snippet view article find links to article

it has been tested in various types of cancer and for non-alcoholic steatohepatitis. Falchook, Gerald; Infante, Jeffrey; Arkenau, Hendrik-Tobias; Patel

ZSP1601 (174 words) [view diff] exact match in snippet view article find links to article

inhibitor developed by Guangdong Raynovent Biotech for nonalcoholic steatohepatitis. Zhu, Xiaoxue; Wu, Min; Wang, Hong; Li, Haijun; Lin, Junjie; Peng,

Claudio Tiribelli (823 words) [view diff] exact match in snippet view article find links to article

population" "Molecular basis and mechanisms of progression of nonalcoholic steatohepatitis (NASH)" "Intestinal Integrity, the Microbiome and Inflammation" Watchko

DA-1241 (274 words) [view diff] exact match in snippet view article find links to article

developed by the South Korean company Dong-A ST for non-alcoholic steatohepatitis and type 2 diabetes. Lee, Seung-Ho; Park, Hansu; Yang, Eun-Kyoung;

FibroTest (1,622 words) [view diff] exact match in snippet view article find links to article

co-infection, alcoholic liver diseases (steatosis and steatohepatitis), and non-alcoholic steatohepatitis (diabetes, overweight, hypertriglyceridemia, hypercholesterolemia

M30-Apoptosense ELISA (738 words) [view diff] exact match in snippet view article find links to article

Measure hepatocyte apoptosis to aid the diagnosis of non-alcoholic steatohepatitis (NASH) and steatosis in patients with hepatitis C virus infection.

Miricorilant (463 words) [view diff] exact match in snippet view article find links to article

antagonist. It was developed by Corcept Therapeutics for nonalcoholic steatohepatitis and weight gain associated with atypical antipsychotics. CORT-108297

Blount's disease (904 words) [view diff] exact match in snippet view article find links to article

mellitus, idiopathic intracranial hypertension (IIH), nonalcoholic steatohepatitis, SCFE, GERD, and hypertension. Blount disease is named after Walter

PXL065 (485 words) [view diff] exact match in snippet view article find links to article

(d-R-pioglitazone) is a drug candidate for the treatment of nonalcoholic steatohepatitis (NASH). It is the deuterium-stabilized (R)-enantiomer of pioglitazone

Cinchonine (194 words) [view diff] exact match in snippet view article find links to article

Receptor Agonist, Lowers Blood Glucose and Ameliorates Non-Alcoholic Steatohepatitis". Drug Design, Development and Therapy. 17: 1417–1432. doi:10.2147/DDDT

SUCNR1 (8,860 words) [view diff] exact match in snippet view article find links to article

hyperlipidemia but not from excessive alcohol consumption. Nonalcoholic steatohepatitis (i.e., NASH), now termed steatotic liver disease (i.e., SLD), is a

Sodium nitrate (1,740 words) [view diff] exact match in snippet view article find links to article

sporadic Alzheimer's disease, diabetes mellitus, and non-alcoholic steatohepatitis". Journal of Alzheimer's Disease. 17 (3): 519–29. doi:10.3233/JAD-2009-1070

Pegipanermin (305 words) [view diff] exact match in snippet view article find links to article

been reported for other neurodegenerative disorders, non-alcoholic steatohepatitis, or solid tumors. Development was discontinued for Parkinson's disease

Formaldehyde dehydrogenase (1,271 words) [view diff] exact match in snippet view article find links to article

antigen. Assessing the gene expression of the ADHs in nonalcoholic steatohepatitis (NASH) patients has shown elevated levels of all ADHs, but primarily

List of hepato-biliary diseases (435 words) [view diff] exact match in snippet view article find links to article

vein granulomatous hepatitis berylliosis sarcoidosis nonalcoholic steatohepatitis (NASH) This may cause fatty liver, hepatitis, fibrosis and sclerosis

S-Nitrosoglutathione (1,518 words) [view diff] exact match in snippet view article find links to article

crucial role in the pathogenesis of liver diseases including steatosis, steatohepatitis, and fibrosis. The ease of reversibility and the interplay of S-nitrosating

LDL receptor (3,036 words) [view diff] exact match in snippet view article find links to article

in the pathophysiology of atherosclerosis, metabolic syndrome, and steatohepatitis. Previously, rare mutations in LDL-genes have been shown to contribute

Alimentiv (355 words) [view diff] exact match in snippet view article find links to article

Summit Clinical Research Announce Collaboration to drive Non-Alcoholic Steatohepatitis (NASH) Clinical Trials". Retrieved 30 April 2024. Cision (3 November

Anandamide (2,365 words) [view diff] exact match in snippet view article find links to article

found in people with nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and liver fibrosis. The American Academy of Dermatology has named

GLP-1 receptor agonist (5,861 words) [view diff] exact match in snippet view article find links to article

approved by the FDA to treat MASH (metabolic dysfunction-associated steatohepatitis) with stage 2 or stage 3 fibrosis of the liver. The mechanism of action

Leronlimab (1,775 words) [view diff] exact match in snippet view article find links to article

pre-clinical study of Leronlimab (PRO 140) to prevent nonalcoholic steatohepatitis with The Cleveland Clinic. In November, the company reported positive

Michael Roden (1,666 words) [view diff] exact match in snippet view article find links to article

Insulin Resistance, Oxidative Stress, and Inflammation in Nonalcoholic Steatohepatitis". Diabetes Care. 41 (6): 1235–1243. doi:10.2337/dc17-1318. ISSN 0149-5992

Gilead Sciences (7,797 words) [view diff] exact match in snippet view article find links to article

agonists in the treatment of liver diseases such as non-alcoholic steatohepatitis. It bought EpiTherapeutics for $65 million. This acquisition gave Gilead

GRAMD1C (362 words) [view diff] exact match in snippet view article find links to article

onset of a form of non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH) in mice. The VASt domain is responsible for binding cholesterol

Amarin Corporation (885 words) [view diff] exact match in snippet view article find links to article

see, if it has an effect on Alzheimer, Colon Cancer, Nonalcoholic Steatohepatitis (NASH), and other diseases. HLS Therapeutics, Amarin´s license partner

Deuterated drug (1,537 words) [view diff] exact match in snippet view article find links to article

rare metabolic diseases, is developing PXL065 to target nonalcoholic steatohepatitis (NASH). The company acquired PXL065 (the deuterium-stabilized (R)-enantiomer

Amycretin (575 words) [view diff] exact match in snippet view article find links to article

(2024). "Management of type 2 diabetes, obesity, or nonalcoholic steatohepatitis with high-dose GLP-1 receptor agonists and GLP-1 receptor-based co-agonists"

Autoimmune hepatitis (3,770 words) [view diff] exact match in snippet view article find links to article

injury on liver biopsy and can help distinguish the two Nonalcoholic steatohepatitis - related medical history and liver biopsy showing fatty infiltration

FM101 (176 words) [view diff] exact match in snippet view article find links to article

Through Regulation of Adenosine a3 Receptor Signaling in Non-alcoholic Steatohepatitis". The FASEB Journal. 34 (S1): 1. doi:10.1096/fasebj.2020.34.s1.03837

VK2735 (176 words) [view diff] exact match in snippet view article find links to article

(2024). "Management of type 2 diabetes, obesity, or nonalcoholic steatohepatitis with high-dose GLP-1 receptor agonists and GLP-1 receptor-based co-agonists"

Ulrike Protzer (1,001 words) [view diff] exact match in snippet view article find links to article

Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes, Cancer Cell (2014)

SH3BP5 (651 words) [view diff] exact match in snippet view article find links to article

Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis". Hepatology. 74 (6): 3127–3145. doi:10.1002/hep

British Transplantation Society (612 words) [view diff] exact match in snippet view article find links to article

Guidelines for liver transplantation for patients with non-alcoholic steatohepatitis. Gut 2012; 61(4): 484-500. "NICE Evidence Search | british transplant

Michael Karin (674 words) [view diff] exact match in snippet view article find links to article

development is promoted by the common metabolic disorder non-alcoholic steatohepatitis (NASH). Using the so-called MUP-uPA mouse they demonstrated that NASH

Free fatty acid receptor 4 (7,964 words) [view diff] exact match in snippet view article find links to article

acting on the succinate-GPR91 signalling pathway for non-alcoholic steatohepatitis (NASH) treatment". Biomedicine & Pharmacotherapy. 144 112298. doi:10

HRS9531 (181 words) [view diff] exact match in snippet view article find links to article

November 2023). "Management of type 2 diabetes, obesity, or nonalcoholic steatohepatitis with high-dose GLP-1 receptor agonists and GLP-1 receptor-based co-agonists"

Cahill cycle (1,756 words) [view diff] exact match in snippet view article find links to article

diseases such as Non-Alcoholic Fatty Liver Disease (NAFLD), Non-Alcoholic steatohepatitis (NASH), and Type 2 Diabetes. A current active area of research is attempting

Acetyl-CoA carboxylase (3,043 words) [view diff] exact match in snippet view article find links to article

company Gilead as part of a combination treatment for non-alcoholic steatohepatitis (NASH), believed to be an increasing cause of liver failure. In addition

Arcturus Therapeutics (1,801 words) [view diff] exact match in snippet view article find links to article

in collaboration with Takeda to develop medicines for non-alcoholic steatohepatitis (NASH) and other gastrointestinal disorders. Lunar-RPL is a project

Nancy Ascher (935 words) [view diff] exact match in snippet view article find links to article

episode focusses on the case of Maria, a patient with a nonalcoholic steatohepatitis and her 22 year old daughter Adriana. Ascher performed the removal

Giaconda (pharmaceutical company) (859 words) [view diff] exact match in snippet view article

could be used to treat primary biliary cirrhosis and non-alcoholic steatohepatitis. Giaconda had initially envisaged using ursodeoxycholic acid as the

Tipelukast (175 words) [view diff] exact match in snippet view article find links to article

1 and LOXL2 mRNA overexpression in an advanced NASH (nonalcoholic steatohepatitis) model: LB-28". Hepatology. 60 (6): 1283A. ISSN 0270-9139. Bascom,

Novo Nordisk (4,069 words) [view diff] exact match in snippet view article find links to article

company focusing on the treatment of metabolic dysfunction-associated steatohepatitis (MASH). Novo Nordisk is involved in government funded collaborative

Insulin resistance (6,810 words) [view diff] exact match in snippet view article find links to article

diabetes: what causes non-alcoholic fatty liver disease and non-alcoholic steatohepatitis?". Journal of Gastroenterology and Hepatology. 25 (10): 1594–7. doi:10

Sirtuin 1 (3,117 words) [view diff] exact match in snippet view article find links to article

repurposed drug, leads to AMPK-mediated inhibition of steatosis and steatohepatitis". European Journal of Pharmacology. 727: 115–24. doi:10.1016/j.ejphar

Thyromimetic (312 words) [view diff] exact match in snippet view article find links to article

2020). "Thyromimetics as emerging therapeutic agents for nonalcoholic steatohepatitis: rationale for the development of resmetirom (MGL-3196)". Expert Opinion

Amira (software) (3,666 words) [view diff] exact match in snippet view article

Werven, J.; Nederveen, A.; Lamers, W.H. (2011). "Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease" (PDF)

Ileal sodium/bile acid cotransporter (1,037 words) [view diff] exact match in snippet view article find links to article

and volixibat, under development for the treatment of nonalcoholic steatohepatitis. Elobixibat Linerixibat Maralixibat Odevixibat Ritivixibat Volixibat

Lipopolysaccharide (7,279 words) [view diff] exact match in snippet view article find links to article

the potential role of endotoxin in the pathogenesis of non-alcoholic steatohepatitis". Obesity Surgery. 17 (10): 1374–1380. doi:10.1007/s11695-007-9243-7

Michael E. Busch (2,656 words) [view diff] exact match in snippet view article find links to article

Center, where he died from complications of pneumonia and non-alcoholic steatohepatitis on April 7. Maryland Governor Larry Hogan ordered flags to be flown

ARO-HSD (287 words) [view diff] exact match in snippet view article find links to article

an RNA interference therapeutic, for the treatment of non-alcoholic steatohepatitis". Journal of Hepatology. 78 (4): 684–692. doi:10.1016/j.jhep.2022.11

Liver (10,357 words) [view diff] exact match in snippet view article find links to article

epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review". Hepatology. 77 (4): 1335–1347. doi:10

Firsocostat (197 words) [view diff] exact match in snippet view article find links to article

acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)". Expert Opinion on Investigational Drugs. 29 (2): 135–141.

Namodenoson (225 words) [view diff] exact match in snippet view article find links to article

double-blind study of namodenoson in non-alcoholic fatty liver disease and steatohepatitis". Alimentary Pharmacology & Therapeutics. 54 (11–12): 1405–1415. doi:10

Free fatty acid receptor (2,806 words) [view diff] exact match in snippet view article find links to article

acting on the succinate-GPR91 signalling pathway for non-alcoholic steatohepatitis (NASH) treatment". Biomedicine & Pharmacotherapy. 144 112298. doi:10

Roche (7,034 words) [view diff] exact match in snippet view article find links to article

inhibitors developed to fight inflammatory diseases like non-alcoholic steatohepatitis and liver fibrosis. In February 2019, the business announced it would

Harrison's Principles of Internal Medicine (4,508 words) [view diff] exact match in snippet view article find links to article

Disease Chapter 336: Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis Chapter 337: Cirrhosis and Its Complications Chapter 338: Liver Transplantation

Metadoxine (1,907 words) [view diff] exact match in snippet view article find links to article

2014). "Metadoxine Versus Placebo for the Treatment of Non-alcoholic Steatohepatitis: A Randomized Controlled Trial". Journal of Clinical and Experimental

Interleukin 6 (7,483 words) [view diff] exact match in snippet view article find links to article

Tsukamoto H (February 2019). "Inflammatory pathways in alcoholic steatohepatitis". Journal of Hepatology. 70 (2): 249–259. doi:10.1016/j.jhep.2018.10

NFE2L1 (3,628 words) [view diff] exact match in snippet view article find links to article

inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia". Proceedings of the National Academy of Sciences

Choline kinase (2,105 words) [view diff] exact match in snippet view article find links to article

phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis". Cell Metabolism. 3 (5): 321–31. doi:10.1016/j.cmet.2006.03.007. PMID 16679290

Glycerol-3-phosphate dehydrogenase 1 (658 words) [view diff] exact match in snippet view article find links to article

(2014). "A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia". Eur. J. Hum. Genet. 22 (10): 1229–32. doi:10

TERN-501 (109 words) [view diff] exact match in snippet view article find links to article

the Treatment of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis". TouchREVIEWS in Endocrinology. 19 (1): 60–70. doi:10.17925/EE.2023

Crohn's disease (18,529 words) [view diff] exact match in snippet view article find links to article

cirrhosis and steatosis. Nonalcoholic fatty liver disease (nonalcoholic steatohepatitis, NAFLD) are relatively common and can slowly progress to end-stage

Detlef Schuppan (1,365 words) [view diff] exact match in snippet view article find links to article

severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis". Gastroenterology. 143 (2): 448–458. doi:10.1053/j.gastro.2012.04

Zeynel Mungan (2,733 words) [view diff] exact match in snippet view article find links to article

fatty liver disease: is there a difference between hepatosteatosis and steatohepatitis? J Gastroenterol Hepatol. 25:619-26 (2010) Yonal O, Akyuz F, Demir

Azemiglitazone (242 words) [view diff] exact match in snippet view article find links to article

Howard C. (April 2020). "Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study". Journal

Vitamin D deficiency (7,809 words) [view diff] exact match in snippet view article find links to article

between vitamin D and non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: results from a meta-analysis". International Journal of Clinical and

ZLY18 (254 words) [view diff] exact match in snippet view article find links to article

and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)". Signal Transduction and Targeted Therapy. 7 (1): 287

Kang-Yell Choi (1,700 words) [view diff] exact match in snippet view article find links to article

focused on developing therapies for conditions such as non-alcoholic steatohepatitis (NASH), hair loss, and diabetic wounds, which are associated with impaired

Plasmodium berghei (2,673 words) [view diff] exact match in snippet view article find links to article

Yu J (September 2016). "C-X-C motif chemokine 10 in non-alcoholic steatohepatitis: role as a pro-inflammatory factor and clinical implication". Expert

Tamoxifen (9,322 words) [view diff] exact match in snippet view article find links to article

Osman MM, Ahmed MH (January 2007). "Tamoxifen-induced non-alcoholic steatohepatitis: where are we now and where are we going?". Expert Opinion on Drug

Alström syndrome (4,115 words) [view diff] exact match in snippet view article find links to article

liver disease is common in AS. This often progresses to non-alcoholic steatohepatitis. Upper and lower respiratory tract infections in childhood, which decrease

Metformin (15,190 words) [view diff] exact match in snippet view article find links to article

patients with non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis: An up-to date systematic review and meta-analysis of randomized controlled

Free fatty acid receptor 1 (7,552 words) [view diff] exact match in snippet view article find links to article

exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis". PLOS ONE. 17 (11) e0277251. Bibcode:2022PLoSO..1777251L. doi:10.1371/journal

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type 2 diabetes, idiopathic intracranial hypertension, nonalcoholic steatohepatitis, Blount disease, slipped capital femoral epiphysis, gastroesophageal

Galectin-3 (3,967 words) [view diff] exact match in snippet view article find links to article

(belapectin) failed phase 3 human clinical trials for nonalcoholic steatohepatitis (NASH). Earlier phase 1 data for belapectin showed increased effectiveness

Gram domain containing 1b (1,454 words) [view diff] exact match in snippet view article find links to article

onset of a form of non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH) in mice. A study tagging SNPs from chronic lymphocytic leukemia

JHU-083 (561 words) [view diff] exact match in snippet view article find links to article

H (December 2022). "Glutaminase 1 blockade alleviates nonalcoholic steatohepatitis via promoting proline metabolism". Biochemical and Biophysical Research

AXA1125 (309 words) [view diff] exact match in snippet view article find links to article

composition impacts metabolism, inflammation, and fibrosis in nonalcoholic steatohepatitis-relevant primary human cell models". Scientific Reports. 11 (1): 11861

15-Hydroxyeicosatetraenoic acid (7,361 words) [view diff] exact match in snippet view article find links to article

Wierling, C (2014). "Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains". PLOS ONE. 9 (10) e111006. Bibcode:2014PLoSO

Osteopontin (8,365 words) [view diff] exact match in snippet view article find links to article

of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis". Toxicology and Applied Pharmacology. 207 (1): 25–38. Bibcode:2005ToxAP

JD5037 (528 words) [view diff] exact match in snippet view article find links to article

receptor inverse agonist, in rats and dogs for treatment of nonalcoholic steatohepatitis". Regulatory Toxicology and Pharmacology. 109 104483. doi:10.1016/j

Gerald I. Shulman (3,058 words) [view diff] exact match in snippet view article find links to article

steatotic liver disease (MASLD), metabolic dysfunction-associated steatohepatitis (MASH), type 2 diabetes (T2D), and related cardiometabolic conditions

Yu-Jui Yvonne Wan (764 words) [view diff] exact match in snippet view article find links to article

which affects the development of metabolic dysfunction-associated steatohepatitis (MASH) and Hepatocellular carcinoma (HCC). She also studies the dietary

Stefano Bellentani (1,138 words) [view diff] exact match in snippet view article find links to article

and their more severe forms, such as cirrhosis and non-alcoholic steatohepatitis (NASH). In a 1982 study, he explored the susceptibility of chronic

Bifidobacterium adolescentis (1,801 words) [view diff] exact match in snippet view article find links to article

2021). "Bifidobacterium adolescentis Alleviates Liver Steatosis and Steatohepatitis by Increasing Fibroblast Growth Factor 21 Sensitivity". Frontiers in

List of drugs granted breakthrough therapy designation (248 words) [view diff] exact match in snippet view article find links to article

exercise, for the treatment of adults with noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate to advanced liver fibrosis (consistent with stages

Alexei Kharitonenkov (2,464 words) [view diff] exact match in snippet view article find links to article

dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis". eBioMedicine. 63 103202. doi:10.1016/j.ebiom.2020.103202. ISSN 2352-3964

Scientist of the Month (393 words) [view diff] exact match in snippet view article find links to article

University Pharmacology Research on mechanisms of fatty liver and steatohepatitis and new therapeutic drug classes March Ham Byeongseung (함병승) Inha University

2024 in science (27,690 words) [view diff] exact match in snippet view article find links to article

phase 3-trialed resmetirom as first medication against nonalcoholic steatohepatitis of the liver (7 Feb), a blood test against heart attacks, the top cause