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Longer titles found: Smooth muscle tumor of uncertain malignant potential (view), Smooth muscle tumour (view), Vascular smooth muscle (view), Congenital smooth muscle hamartoma (view), Anti-smooth muscle antibody (view), Multisystemic smooth muscle dysfunction syndrome (view)

searching for Smooth muscle 299 found (2578 total)

alternate case: smooth muscle

Muscarinic acetylcholine receptor M3 (1,762 words) [view diff] exact match in snippet view article find links to article

homoestasis by modulating insulin secretion. In general, they cause smooth muscle contraction and increased glandular secretions. They are unresponsive

PDGFB (434 words) [view diff] exact match in snippet view article find links to article

of smooth muscle cell migration positive regulation of smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell

ACTG2 (1,017 words) [view diff] exact match in snippet view article find links to article

Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene. Actins are highly conserved proteins that are involved in

Myosin light-chain kinase (1,731 words) [view diff] exact match in snippet view article find links to article

filaments, keeping it in place. Four different MYLK isoforms exist: MYLK1 – smooth muscle MYLK2 – skeletal MYLK3 – cardiac MYLK4 – novel These enzymes are important

Spiral artery (173 words) [view diff] exact match in snippet view article find links to article

for uteroplacental blood flow during pregnancy, involving: Loss of smooth muscle and elastic lamina from the vessel wall. 5-10 fold dilation at the mouth

HMOX1 (679 words) [view diff] exact match in snippet view article find links to article

apoptotic process cellular iron ion homeostasis negative regulation of smooth muscle cell proliferation cellular response to heat intracellular signal transduction

Tachykinin receptor 2 (1,178 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in gastric mucosa muscle layer of sigmoid colon smooth muscle tissue left uterine tube epithelium of colon testicle body of uterus

Alpha blocker (3,194 words) [view diff] exact match in snippet view article find links to article

receptors in the arteries and smooth muscle. Ultimately, depending on the type of alpha receptor, this relaxes the smooth muscle or blood vessels, which increases

Neuromedin U (1,344 words) [view diff] exact match in snippet view article find links to article

mammals, which has a number of diverse functions including contraction of smooth muscle, regulation of blood pressure, pain perception, appetite, bone growth

EEF1B2P2 (64 words) [view diff] exact match in snippet view article find links to article

skeletal muscle tissue rectum stromal cell of endometrium muscle of leg smooth muscle tissue triceps surae gastrocnemius muscle n/a More reference expression

Venule (439 words) [view diff] exact match in snippet view article find links to article

post-capillary venules increase in diameter to 50 μm they can incorporate smooth muscle and are known as muscular venules. Veins contain approximately 70% of

Muscarinic acetylcholine receptor M2 (2,093 words) [view diff] exact match in snippet view article find links to article

airway smooth muscle. Synergistically, activation of the M3 receptors, which couple to Gq, stimulates contraction of the airway smooth muscle. A Dutch

Angiotensin (3,205 words) [view diff] exact match in snippet view article find links to article

upon vascular smooth muscle cells (with downstream IP3-dependent mechanism causing a rise in intracellular Ca2+ to effect smooth muscle excitation-contraction

Cromakalim (370 words) [view diff] exact match in snippet view article find links to article

hypertension as it will relax vascular smooth muscle to lower blood pressure. Hyperpolarisation of smooth muscle cell membranes pulls their membrane potential

PRKG1 (1,315 words) [view diff] exact match in snippet view article find links to article

G (Dec 2003). "Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure". Nature Medicine. 9 (12): 1506–12. doi:10

Endothelin 1 (380 words) [view diff] exact match in snippet view article find links to article

surface receptor signaling pathway multicellular organism aging artery smooth muscle contraction cellular response to interferon-gamma positive regulation

OR56B4 (243 words) [view diff] exact match in snippet view article find links to article

expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad smooth muscle tissue mucosa of transverse colon monocyte rectum appendix islet of

Mir-145 (1,630 words) [view diff] exact match in snippet view article find links to article

PMC 2770572. PMID 19843336. Zhang C (Nov 2009). "MicroRNA-145 in vascular smooth muscle cell biology: a new therapeutic target for vascular disease". Cell Cycle

P2RX1 (977 words) [view diff] exact match in snippet view article find links to article

Expressed in smooth muscle and platelets. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible

IGFBP5 (904 words) [view diff] exact match in snippet view article find links to article

lumen extracellular space Biological process negative regulation of smooth muscle cell proliferation negative regulation of translation positive regulation

Alpha-adrenergic agonist (1,325 words) [view diff] exact match in snippet view article find links to article

the action of epinephrine and norepinephrine signaling in the heart, smooth muscle and central nervous system, with norepinephrine being the highest affinity

OR5K1 (300 words) [view diff] exact match in snippet view article find links to article

muscle of thigh apex of heart ventricle of the heart left ventricle smooth muscle tissue n/a More reference expression data BioGPS More reference expression

OR2A5 (285 words) [view diff] exact match in snippet view article find links to article

rectum muscle tissue Descending thoracic aorta skeletal muscle tissue smooth muscle tissue muscle of thigh n/a More reference expression data BioGPS n/a

OR2T33 (279 words) [view diff] exact match in snippet view article find links to article

testicle gonad monocyte bone marrow blood left lobe of thyroid gland smooth muscle tissue prefrontal cortex right lobe of thyroid gland primary visual

OR2C3 (376 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in gonad ganglionic eminence gastric mucosa smooth muscle tissue placenta testicle endometrium right testis gallbladder islet

Ryanodine (275 words) [view diff] exact match in snippet view article find links to article

ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells. It binds with such high affinity to the receptor

Ryanodine (275 words) [view diff] exact match in snippet view article find links to article

ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells. It binds with such high affinity to the receptor

CALCRL (2,062 words) [view diff] exact match in snippet view article find links to article

functional adrenomedullin receptor in human endothelial and vascular smooth muscle cells". FEBS Letters. 448 (1): 111–114. Bibcode:1999FEBSL.448..111K

Macitentan (963 words) [view diff] exact match in snippet view article find links to article

release, ET-1 can bind to the ET receptors that are expressed on arterial smooth muscle cells and fibroblasts in the lungs. ET receptors are G protein coupled

Beta-adrenergic agonist (894 words) [view diff] exact match in snippet view article find links to article

epinephrine- and norepinephrine- signaling, in the heart and lungs, and in smooth muscle tissue; epinephrine expresses the higher affinity. The activation of

Submucosal plexus (304 words) [view diff] exact match in snippet view article find links to article

Its function is to innervate cells in the epithelial layer and the smooth muscle of the muscularis mucosae. 14% of submucosal plexus neurons are sensory

Lactiferous duct (469 words) [view diff] exact match in snippet view article find links to article

influence of hormones, the milk is moved to the nipple by the action of smooth muscle contractions along the ductal system to the tip of the nipple. They

List of human cell types derived from the germ layers (479 words) [view diff] no match in snippet view article find links to article

This is a list of cells in humans derived from the three embryonic germ layers – ectoderm, mesoderm, and endoderm. Trichocyte Keratinocyte Gonadotrope

Integrin alpha 2 (688 words) [view diff] exact match in snippet view article find links to article

regulation of smooth muscle contraction response to muscle activity positive regulation of cell adhesion positive regulation of smooth muscle cell proliferation

LRP11 (79 words) [view diff] exact match in snippet view article find links to article

Achilles tendon superior frontal gyrus Brodmann area 9 prefrontal cortex smooth muscle tissue primary visual cortex corpus callosum Top expressed in dentate

Cyclic guanosine monophosphate (2,132 words) [view diff] exact match in snippet view article find links to article

external cell surface. Through protein kinases activation, cGMP can relax smooth muscle. cGMP concentration in urine can be measured for kidney function and

N-acetyltransferase 2 (586 words) [view diff] exact match in snippet view article find links to article

transverse colon mucosa of sigmoid colon rectum amniotic fluid appendix smooth muscle tissue Top expressed in morula embryo embryo blastocyst pineal gland

Spermatheca (548 words) [view diff] exact match in snippet view article find links to article

the end of each gonad. The C. elegans spermatheca is made up of 24 smooth muscle-like cells that form a stretchable tubular structure. Actin filaments

Fasudil (1,191 words) [view diff] exact match in snippet view article find links to article

phosphatase, thus decreasing MLC phosphatase activity and enhancing vascular smooth muscle contraction. Angiotensin-converting enzyme (ACE) is an enzyme that catalyzes

OR2F1 (534 words) [view diff] exact match in snippet view article find links to article

Human Mouse (ortholog) Top expressed in tibial arteries apex of heart smooth muscle tissue sural nerve placenta anterior cingulate cortex ascending aorta

Drofenine (163 words) [view diff] exact match in snippet view article find links to article

Drofenine is an antimuscarinic antispasmodic drug used for relaxing smooth muscle, thereby treating conditions, such as: dysmenorrhea, and pain in the

KCNMB2 (1,062 words) [view diff] exact match in snippet view article find links to article

calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. BK channels can contain two distinct

HEY2 (1,410 words) [view diff] exact match in snippet view article find links to article

et al. (November 2005). "HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box". Arteriosclerosis

Leukotriene D4 (80 words) [view diff] exact match in snippet view article find links to article

leukotrienes. Its main function in the body is to induce the contraction of smooth muscle, resulting in bronchoconstriction and vasoconstriction. It also increases

Collagen, type XXII, alpha 1 (83 words) [view diff] exact match in snippet view article find links to article

pituitary tibia corpus epididymis seminal vesicula ganglionic eminence smooth muscle tissue prostate synovial joint islet of Langerhans Top expressed in

Myoepithelial cell (453 words) [view diff] exact match in snippet view article find links to article

generally beneath the luminal cells. These may be positive for alpha smooth muscle actin and can contract and expel the secretions of exocrine glands.

Calcium-binding mitochondrial carrier protein SCaMC-1 (370 words) [view diff] exact match in snippet view article find links to article

Langerhans monocyte Achilles tendon endometrium mucosa of transverse colon smooth muscle tissue placenta gallbladder Top expressed in left colon transitional

Nuclear receptor 4A3 (1,330 words) [view diff] exact match in snippet view article find links to article

is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation". The Journal of Biological Chemistry. 281 (44):

Trepibutone (113 words) [view diff] exact match in snippet view article find links to article

of the bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract to lower internal pressure of the gallbladder

Endothelin A receptor (1,183 words) [view diff] exact match in snippet view article find links to article

endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells]". Japanese Circulation Journal. 56 (Suppl 5): 1303–7. doi:10

Purinergic receptor (1,611 words) [view diff] exact match in snippet view article find links to article

vasodilation, respectively, in the smooth muscle of some arteries. They had been observed in blood vessels, smooth muscle, heart, hepatocytes, and parotid

Ferid Murad (1,112 words) [view diff] exact match in snippet view article find links to article

pharmacologist, His research demonstrated that nitroglycerin relaxes smooth muscle by releasing nitric oxide into the body. This work led to him sharing

ATP2B4 (1,161 words) [view diff] exact match in snippet view article find links to article

vein tail of epididymis body of uterus myometrium epithelium of colon smooth muscle tissue left uterine tube muscle layer of sigmoid colon superficial temporal

Vasoactive intestinal peptide (2,732 words) [view diff] exact match in snippet view article find links to article

increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gallbladder. In humans, the vasoactive intestinal

Mir-1 microRNA precursor family (3,291 words) [view diff] exact match in snippet view article find links to article

of smooth muscle cells from embryonic stem cell derived cultures, MiR-1 is required; as its loss of function resulted in a reduction in smooth muscle cell

ALPI (1,157 words) [view diff] exact match in snippet view article find links to article

ileum mucosa of transverse colon rectum human kidney muscle tissue smooth muscle tissue appendix gallbladder Top expressed in duodenum embryo jejunum

Extraglomerular mesangial cell (238 words) [view diff] exact match in snippet view article find links to article

found outside the glomerulus, near the vascular pole. They resemble smooth muscle cells and play a role in renal autoregulation of blood flow to the kidney

Fenpiverinium (259 words) [view diff] exact match in snippet view article find links to article

either nimesulide or metamizole in Eastern Europe and India to treat smooth muscle spasms and pain. The combination with metamizole was removed from the

Gastrin-releasing peptide receptor (1,379 words) [view diff] exact match in snippet view article find links to article

central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent

OR51E2 (847 words) [view diff] exact match in snippet view article find links to article

arteries prostate muscle layer of sigmoid colon right coronary artery smooth muscle tissue transverse colon rectum left coronary artery Top expressed in

GANAB (1,080 words) [view diff] exact match in snippet view article find links to article

ovary right lobe of thyroid gland body of pancreas canal of the cervix smooth muscle tissue body of uterus Top expressed in cumulus cell ventricular zone

Neurogenin-3 (1,280 words) [view diff] exact match in snippet view article find links to article

transverse colon duodenum hippocampus proper right adrenal cortex rectum smooth muscle tissue right coronary artery left adrenal gland left adrenal cortex

DYNC1I2 (721 words) [view diff] exact match in snippet view article find links to article

tendon ganglionic eminence C1 segment ventricular zone sural nerve smooth muscle tissue islet of Langerhans popliteal artery tibial arteries Descending

Cimetropium bromide (316 words) [view diff] exact match in snippet view article find links to article

antagonist, it inhibits acetylcholine-mediated contractions in the smooth muscle of the digestive tract, thereby reducing spasms and alleviating abdominal

Ipidacrine (246 words) [view diff] exact match in snippet view article find links to article

but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle. List of Russian drugs Kojima J, Onodera K, Ozeki M, Nakayarna K (1998)

Mir-143 (1,525 words) [view diff] exact match in snippet view article find links to article

important role in smooth muscle cell fate. It is co-transcribed with miR-145 in cardiac progenitors before becoming vascular smooth muscle cells (VSMCs).

Integrin alpha 5 (444 words) [view diff] exact match in snippet view article find links to article

Descending thoracic aorta stromal cell of endometrium ascending aorta smooth muscle tissue left uterine tube upper lobe of left lung right lung Top expressed

Alpha-actinin-4 (1,463 words) [view diff] exact match in snippet view article find links to article

binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where

Obstructive lung disease (1,279 words) [view diff] exact match in snippet view article find links to article

and larger bronchioles, often because of excessive contraction of the smooth muscle itself. It is generally characterized by inflamed and easily collapsible

GNA14 (171 words) [view diff] exact match in snippet view article find links to article

expressed in secondary oocyte bronchial epithelial cell testicle C1 segment smooth muscle tissue left lobe of thyroid gland tail of epididymis olfactory zone

General visceral afferent fiber (728 words) [view diff] exact match in snippet view article find links to article

insensitive to cutting, crushing or burning; however, excessive tension in smooth muscle and some pathological conditions produce visceral pain (referred pain)

SPEG (713 words) [view diff] exact match in snippet view article find links to article

this gene is thought to serve as a marker for differentiated vascular smooth muscle cells which may have a role in regulating growth and differentiation

MMP26 (994 words) [view diff] exact match in snippet view article find links to article

prostate renal cortex myometrium hepatobiliary system skeletal muscle smooth muscle tissue n/a More reference expression data BioGPS More reference expression

Alpha-2B adrenergic receptor (1,755 words) [view diff] exact match in snippet view article find links to article

(Jan 2004). "Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells". American Journal of Physiology. Heart and Circulatory Physiology

Triflin (580 words) [view diff] exact match in snippet view article find links to article

(Trimeresurus flavoviridis). Triflin reduces high potassium-induced smooth muscle contraction, suggesting a blocking effect on L-type calcium channels

EIF3I (1,134 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in islet of Langerhans ganglionic eminence smooth muscle tissue gastrocnemius muscle rectum left adrenal gland right adrenal

EIF3B (952 words) [view diff] exact match in snippet view article find links to article

left uterine tube gastrocnemius muscle ventricular zone right ovary smooth muscle tissue Top expressed in epiblast spermatid ventricular zone yolk sac

Michelin tire baby syndrome (441 words) [view diff] exact match in snippet view article find links to article

cleft palate, genital anomalies, mild developmental delay, ureterocele, smooth muscle hamartoma, nevus lipomatosus, Laron syndrome (dwarfism with high growth

Prokineticin receptor (145 words) [view diff] exact match in snippet view article find links to article

different gene (PROKR1, PROKR2). These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis. Lin DC, Bullock CM, Ehlert FJ, Chen JL

MEF2B (1,118 words) [view diff] exact match in snippet view article find links to article

involved in smooth muscle myosin heavy chain (SMHC) gene regulation. Overexpression of MEF2B will activate the SMHC promoter in smooth muscle when it is

Metarteriole (226 words) [view diff] exact match in snippet view article find links to article

capillaries. Instead of a continuous tunica media, they have individual smooth muscle cells placed a short distance apart, each forming a precapillary sphincter

60S ribosomal protein L4 (869 words) [view diff] exact match in snippet view article find links to article

eminence cartilage tissue ventricular zone vulva tail of epididymis glutes smooth muscle tissue superficial temporal artery caput epididymis Top expressed in

COPZ1 (523 words) [view diff] exact match in snippet view article find links to article

ganglionic eminence rectum monocyte right adrenal gland gallbladder smooth muscle tissue Top expressed in yolk sac dermis duodenum right kidney epithelium

Glomus tumor (1,047 words) [view diff] exact match in snippet view article find links to article

anastomotic vessel, and collecting venule. Glomus tumors are modified smooth muscle cells that control the thermoregulatory function of dermal glomus bodies

Latisemin (445 words) [view diff] exact match in snippet view article find links to article

nucleotide-gated ion channels and blocks L-type calcium channels, thereby reducing smooth muscle contraction. Latisemin is a component of the venom produced by the Erabu

Epiregulin (1,149 words) [view diff] exact match in snippet view article find links to article

Cheng X, Pawlowski JE, et al. (1999). "Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin"

MMP11 (913 words) [view diff] exact match in snippet view article find links to article

stromal cell of endometrium canal of the cervix right uterine tube smooth muscle tissue gallbladder left ventricle ganglionic eminence right coronary

Mitochondrial ribosomal protein L18 (628 words) [view diff] exact match in snippet view article find links to article

muscle of thigh anterior cingulate cortex mucosa of transverse colon smooth muscle tissue prefrontal cortex C1 segment Top expressed in blastocyst primary

DNAJC14 (451 words) [view diff] exact match in snippet view article find links to article

Langerhans mucosa of ileum stromal cell of endometrium granulocyte smooth muscle tissue monocyte tibialis anterior muscle appendix rectum prefrontal

60S ribosomal protein L7 (1,128 words) [view diff] exact match in snippet view article find links to article

left ovary gastric mucosa right ovary canal of the cervix monocyte smooth muscle tissue body of uterus Top expressed in epiblast ventricular zone ganglionic

Tetraspanin 18 (344 words) [view diff] exact match in snippet view article find links to article

atrium myocardium of left ventricle right auricle of heart apex of heart smooth muscle tissue ganglionic eminence right adrenal gland right adrenal cortex

Isoxsuprine (457 words) [view diff] exact match in snippet view article find links to article

adrenoreceptor agonist that causes direct relaxation of uterine and vascular smooth muscle via β2 receptors. Isoxsuprine is used in humans for treatment of premature

40S ribosomal protein S7 (737 words) [view diff] exact match in snippet view article find links to article

ventricular zone islet of Langerhans right ovary rectum lymph node smooth muscle tissue ganglionic eminence Top expressed in ganglionic eminence ventricular

Alpha-2C adrenergic receptor (1,541 words) [view diff] exact match in snippet view article find links to article

NA (2004). "Regulation of alpha(2)-adrenoceptors in human vascular smooth muscle cells". Am. J. Physiol. Heart Circ. Physiol. 286 (1): H59–67. doi:10

Endothelin 3 (1,004 words) [view diff] exact match in snippet view article find links to article

"Secretion of endothelin-1 and endothelin-3 by human cultured vascular smooth muscle cells". Br. J. Pharmacol. 114 (2): 551–7. doi:10.1111/j.1476-5381.1995

Trolnitrate (67 words) [view diff] exact match in snippet view article find links to article

Trolnitrate dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates. "Medical

Baroreceptor (1,083 words) [view diff] exact match in snippet view article find links to article

autonomic reflexes that in turn influence cardiac output and vascular smooth muscle to influence vascular resistance. Baroreceptors act immediately as part

60S ribosomal protein L10a (800 words) [view diff] exact match in snippet view article find links to article

uterine tube left ovary right ovary canal of the cervix body of uterus smooth muscle tissue skin of abdomen left uterine tube skin of leg ganglionic eminence

FGF9 (1,521 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration negative regulation

Hyperaemia (952 words) [view diff] exact match in snippet view article find links to article

tissues. The myogenic effect refers to the inherent attempt of vascular smooth muscle surrounding arterioles and arteries to maintain the tension in the wall

Insulin-like growth factor 1 (4,615 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process negative

Cysteine-rich secretory protein (927 words) [view diff] exact match in snippet view article find links to article

are also found in a variety of snake venoms where they inhibit both smooth muscle contraction and cyclic nucleotide-gated ion channels. CRISPs contain

Clear cell papillary renal cell carcinoma (213 words) [view diff] no match in snippet view article find links to article

Clear cell papillary renal cell tumour (CCPRCT) is a rare subtype of renal cell carcinoma (RCC) that has microscopic morphologic features of papillary

MMP19 (964 words) [view diff] exact match in snippet view article find links to article

ascending aorta stromal cell of endometrium Descending thoracic aorta smooth muscle tissue right ovary Top expressed in liver stroma of bone marrow blood

Corydaline (405 words) [view diff] exact match in snippet view article find links to article

induced pain. Additionally, this compound may inhibit mast cell-dependent smooth muscle contraction of the aorta. It inhibits thrombin-induced platelet aggregation

Heterotrimeric G protein (1,237 words) [view diff] exact match in snippet view article find links to article

H4, Dopamine D2-like receptors, type 2 cannabinoid receptors (CB2) Smooth muscle contraction, depress neuronal activity, interleukin secretion by human

CENPI (650 words) [view diff] exact match in snippet view article find links to article

zone gonad ganglionic eminence testicle stromal cell of endometrium smooth muscle tissue bone marrow rectum trabecular bone Top expressed in hand tail

U46619 (181 words) [view diff] exact match in snippet view article find links to article

thromboxane A2, including shape change and aggregation of platelets and smooth muscle contraction. U46619 is a vasoconstrictor that mimics the hydroosmotic

GATA6 (1,413 words) [view diff] exact match in snippet view article find links to article

p300 protein as a coactivator of GATA-6 in the transcription of the smooth muscle-myosin heavy chain gene". J. Biol. Chem. 275 (33): 25330–5. doi:10.1074/jbc

Mucin 2 (316 words) [view diff] exact match in snippet view article find links to article

mucosa of transverse colon rectum duodenum appendix epithelium of colon smooth muscle tissue olfactory zone of nasal mucosa muscle layer of sigmoid colon

Pitrakinra (780 words) [view diff] exact match in snippet view article find links to article

inflammatory cells (dendritic cells, Th2 cells, B cells) and structural cells (smooth muscle, endothelium, epithelium) that express IL-4Rα. The drug has been applied

Mucin 17 (434 words) [view diff] exact match in snippet view article find links to article

expressed in duodenum rectum testicle transverse colon right lobe of liver smooth muscle tissue appendix sural nerve islet of Langerhans right lung n/a More

Prostaglandin receptor (879 words) [view diff] exact match in snippet view article find links to article

classification as contractile (i.e. contracting smooth muscle), relaxant (i.e. relaxing smooth muscle), or inhibitory (i.e. inhibiting adenyl cyclase

Alpha-actinin-1 (1,374 words) [view diff] exact match in snippet view article find links to article

binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where

GABRR2 (613 words) [view diff] exact match in snippet view article find links to article

muscle tissue deltoid muscle sperm tibialis anterior muscle spleen smooth muscle tissue Top expressed in neural layer of retina embryo embryo muscle

Atrial natriuretic peptide receptor (360 words) [view diff] exact match in snippet view article find links to article

which will then induce smooth muscle relaxation. This is particularly important in the vasculature, where vascular smooth muscle will bind ANP released

Cathepsin O (400 words) [view diff] exact match in snippet view article find links to article

expressed in Achilles tendon gallbladder endometrium right coronary artery smooth muscle tissue placenta gastric mucosa liver duodenum monocyte Top expressed

ADAMTS1 (1,543 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration Sources:Amigo /

KRT37 (232 words) [view diff] exact match in snippet view article find links to article

in gonad skin of abdomen skin of leg canal of the cervix ectocervix smooth muscle tissue vagina wall of uterus endometrium right lung n/a More reference

60S ribosomal protein L6 (1,074 words) [view diff] exact match in snippet view article find links to article

of Langerhans pituitary gland Achilles tendon lymph node left ovary smooth muscle tissue monocyte n/a More reference expression data BioGPS n/a Gene ontology

Solabegron (546 words) [view diff] exact match in snippet view article find links to article

and acquired by AltheRx in March 2011. Solabegron relaxes the bladder smooth muscle by stimulating β3 adrenoceptors, a novel mechanism compared with older

Platelet-activating factor receptor (1,097 words) [view diff] exact match in snippet view article find links to article

system smooth muscle contraction positive regulation of tumor necrosis factor production inflammatory response positive regulation of smooth muscle contraction

Superior vena cava (765 words) [view diff] exact match in snippet view article find links to article

the middle zone consisting of few smooth muscle fibers; this differs from the longitudinal bundles of smooth muscle found in the same zone of the inferior

Vitronectin (1,046 words) [view diff] exact match in snippet view article find links to article

matrix organization smooth muscle cell-matrix adhesion regulation of complement activation positive regulation of smooth muscle cell migration negative

Betacellulin (1,733 words) [view diff] exact match in snippet view article find links to article

nitrogen signaling in retinal pigment epithelial cells and vascular smooth muscle cells. While many studies attest a role for betacellulin in the differentiation

MAS1L (283 words) [view diff] exact match in snippet view article find links to article

RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in smooth muscle tissue gallbladder rectum mucosa of transverse colon subcutaneous adipose

Anipamil (709 words) [view diff] exact match in snippet view article find links to article

may have on the smooth muscle cell in hypertensive rabbits. After using monoclonal antimyosin antibodies to recognize smooth muscle, nonmuscle myosin

GPR20 (198 words) [view diff] exact match in snippet view article find links to article

popliteal artery tibial arteries left coronary artery gastric mucosa smooth muscle tissue Descending thoracic aorta left uterine tube Top expressed in

Glutathione peroxidase 8 (138 words) [view diff] exact match in snippet view article find links to article

expressed in stromal cell of endometrium tibia germinal epithelium placenta smooth muscle tissue Achilles tendon parietal pleura gonad synovial membrane corpus

Heat shock protein 47 (1,584 words) [view diff] exact match in snippet view article find links to article

reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells". The Journal of Biological Chemistry. 277 (41): 38571–38578.

MRGPRX3 (284 words) [view diff] exact match in snippet view article find links to article

mucosa lactiferous gland urinary bladder vagina ectocervix skin of leg smooth muscle tissue tibial nerve n/a More reference expression data BioGPS n/a Gene

Anipamil (709 words) [view diff] exact match in snippet view article find links to article

may have on the smooth muscle cell in hypertensive rabbits. After using monoclonal antimyosin antibodies to recognize smooth muscle, nonmuscle myosin

Felypressin (130 words) [view diff] exact match in snippet view article find links to article

Liver, Anterior Pituitary, Muscle (both vascular and non-vascular smooth muscle), and Platelets (CLAMP). Another example of a V1 agonist is terlipressin

Vasomotor (424 words) [view diff] exact match in snippet view article find links to article

extracellular fluid surrounding the smooth muscle (tunica media) from the terminal knob of the axon. The smooth muscle cell membranes have α and β-adrenergic

PDGFRB (3,407 words) [view diff] exact match in snippet view article find links to article

either PDGFRB, or PDGF-B reduces the number of pericytes and vascular smooth muscle cells, and thereby compromises the integrity and/or functionality of

Gastrin-releasing peptide (1,461 words) [view diff] exact match in snippet view article find links to article

central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. GRP is located

MRGPRX2 (370 words) [view diff] exact match in snippet view article find links to article

adipose tissue rectum urinary bladder fundus vagina gastric mucosa smooth muscle tissue Top expressed in muscle of thigh zone of skin quadriceps femoris

PDCD4 (1,041 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell apoptotic process Sources:Amigo

60S ribosomal protein L7a (1,082 words) [view diff] exact match in snippet view article find links to article

adrenal cortex right ovary right adrenal gland right adrenal cortex smooth muscle tissue pituitary gland Top expressed in epiblast ganglionic eminence

ADAM9 (1,234 words) [view diff] exact match in snippet view article find links to article

expressed in stromal cell of endometrium islet of Langerhans gallbladder smooth muscle tissue right lung Descending thoracic aorta Achilles tendon ascending

ADGRL4 (443 words) [view diff] exact match in snippet view article find links to article

pleura parietal pleura subcutaneous adipose tissue Achilles tendon smooth muscle tissue lower lobe of lung gallbladder vena cava mammary gland Top expressed

Autonomic (81 words) [view diff] exact match in snippet view article find links to article

nervous system, a division of the peripheral nervous system that supplies smooth muscle and glands, and thus influences the function of internal organs Autonomic

CDH11 (1,192 words) [view diff] exact match in snippet view article find links to article

Achilles tendon decidua left ovary right ovary germinal epithelium smooth muscle tissue Top expressed in calvaria vas deferens dermis body of femur Gonadal

AP3B1 (989 words) [view diff] exact match in snippet view article find links to article

rectum stromal cell of endometrium beta cell mucosa of transverse colon smooth muscle tissue Top expressed in choroid plexus of fourth ventricle Ileal epithelium

Urokinase (2,291 words) [view diff] exact match in snippet view article find links to article

proliferation smooth muscle cell migration regulation of wound healing chemotaxis regulation of cell adhesion mediated by integrin regulation of smooth muscle cell

MKL1 (1,205 words) [view diff] exact match in snippet view article find links to article

the transcription factor serum response factor, a key regulator of smooth muscle cell differentiation, in an interaction mediated by its Basic domain

Flavoxate (269 words) [view diff] exact match in snippet view article find links to article

Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by antagonizing muscarinic receptors. Flavoxate is used

P2RX2 (620 words) [view diff] exact match in snippet view article find links to article

mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified

FKBP9 (363 words) [view diff] exact match in snippet view article find links to article

in stromal cell of endometrium epithelium of colon Achilles tendon smooth muscle tissue placenta gallbladder Descending thoracic aorta subcutaneous adipose

CXCL2 (664 words) [view diff] exact match in snippet view article find links to article

testing the role of CXCL2, CXCL3, and CXCL1 in the migration of airway smooth muscle cells (ASMCs) migration which plays a significant role in asthma. The

CTGF (1,538 words) [view diff] exact match in snippet view article find links to article

the dermis, kidney, and lung, and deletion of Ctgf in fibroblasts and smooth muscle cells greatly reduces bleomycin-induced skin fibrosis. In addition to

Niludipine (77 words) [view diff] exact match in snippet view article find links to article

heart-lung. It was found to produce a calcium antagonistic effect on the smooth muscle of hearts of canines and guinea pigs inhibiting myocardial oxidative

KCNG1 (544 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium

INSL4 (611 words) [view diff] exact match in snippet view article find links to article

corpus epididymis stromal cell of endometrium cecum appendix liver smooth muscle tissue right lobe of liver popliteal artery n/a More reference expression

MMP14 (1,064 words) [view diff] exact match in snippet view article find links to article

gastric mucosa gallbladder canal of the cervix body of uterus ectocervix smooth muscle tissue right coronary artery popliteal artery tibial arteries Top expressed

MRGPRD (246 words) [view diff] exact match in snippet view article find links to article

tube popliteal artery tibial arteries right coronary artery cerebellum smooth muscle tissue cerebellar cortex Top expressed in spinal cord pons Gray matter

Mometasone/formoterol (612 words) [view diff] exact match in snippet view article find links to article

works by decreasing inflammation while formoterol works by relaxing smooth muscle in the airways. The combination was approved for medical use in the

Ductus arteriosus (916 words) [view diff] exact match in snippet view article find links to article

maintaining the openness of the ductus arteriosus (by dilation of vascular smooth muscle) throughout the fetal period. Prostaglandin E2 (PGE2), produced by both

CHRNB4 (998 words) [view diff] exact match in snippet view article find links to article

cholinergic synapse Biological process smooth muscle contraction locomotory behavior regulation of smooth muscle contraction protein heterooligomerization

Laminin, alpha 4 (1,232 words) [view diff] exact match in snippet view article find links to article

Top expressed in tibial nerve left uterine tube epithelium of colon smooth muscle tissue parietal pleura body of uterus sural nerve muscle layer of sigmoid

Leukemia inhibitory factor (1,587 words) [view diff] exact match in snippet view article find links to article

bladder appendix pancreatic ductal cell mucosa of transverse colon smooth muscle tissue mucosa of paranasal sinus Top expressed in endometrium Glandular

DCP1B (282 words) [view diff] exact match in snippet view article find links to article

Human Mouse (ortholog) Top expressed in muscle layer of sigmoid colon smooth muscle tissue body of uterus gonad myometrium right adrenal gland right adrenal

AKT3 (1,197 words) [view diff] exact match in snippet view article find links to article

"Enhanced stimulation of Akt-3/protein kinase B-gamma in human aortic smooth muscle cells". Biochem. Biophys. Res. Commun. 283 (1): 158–63. Bibcode:2001BBRC

SMN2 (1,354 words) [view diff] exact match in snippet view article find links to article

Human Mouse (ortholog) Top expressed in epithelium of colon endometrium smooth muscle tissue right uterine tube olfactory zone of nasal mucosa rectum bone

SIGLEC6 (2,034 words) [view diff] exact match in snippet view article find links to article

pancreatic ductal cell gallbladder mucosa of ileum lymph node appendix smooth muscle tissue n/a More reference expression data BioGPS n/a Gene ontology Molecular

Heparin-binding EGF-like growth factor (2,598 words) [view diff] exact match in snippet view article find links to article

HB-EGF, which influences the mitogenicity and chemotactic factors for smooth muscle cells and fibroblasts. The transmembrane form of HB-EGF is the unique

SIGLEC6 (2,034 words) [view diff] exact match in snippet view article find links to article

pancreatic ductal cell gallbladder mucosa of ileum lymph node appendix smooth muscle tissue n/a More reference expression data BioGPS n/a Gene ontology Molecular

KIT (gene) (4,133 words) [view diff] exact match in snippet view article

negative for markers such as desmin and S-100, which are positive in smooth muscle and neural tumors, which have a similar appearance. In GISTs, KIT staining

Neointima (140 words) [view diff] exact match in snippet view article find links to article

stent placement. Formation of neointima occurs due to proliferation of smooth muscle cells as well as macrophages. Komatsu, Ryushi; Ueda, Makiko; Naruko

Bone morphogenetic protein 8A (282 words) [view diff] exact match in snippet view article find links to article

periodontal fiber tibia C1 segment left ovary right ovary islet of Langerhans smooth muscle tissue tibial nerve Top expressed in decidua gastrula intestinal villus

ANO1 (1,437 words) [view diff] exact match in snippet view article find links to article

additionally Anoctamin-1 is apical iodide channel. It is expressed in smooth muscle, epithelial cells, vomeronasal neurons, olfactory sustentacular cells

MYH7B (441 words) [view diff] exact match in snippet view article find links to article

brachii lateral nuclear group of thalamus sperm Top expressed in vascular smooth muscle lens neural layer of retina left ventricle soleus muscle vasculature

UBE2Z (1,021 words) [view diff] exact match in snippet view article find links to article

cell of endometrium cartilage tissue corpus epididymis mucosa of ileum smooth muscle tissue beta cell granulocyte nipple lymph node Top expressed in choroid

PDGFD (793 words) [view diff] exact match in snippet view article find links to article

to transforming growth factor beta stimulus positive regulation of smooth muscle cell chemotaxis positive regulation of MAP kinase activity positive

TRIB1 (924 words) [view diff] exact match in snippet view article find links to article

(June 2007). "Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways". The Journal of Biological Chemistry

Bone morphogenetic protein 4 (5,032 words) [view diff] exact match in snippet view article find links to article

prostate gland morphogenesis positive regulation of ERK1 and ERK2 cascade smooth muscle tissue development BMP signaling pathway involved in heart induction

MS4A2 (1,019 words) [view diff] exact match in snippet view article find links to article

gallbladder testicle rectum monocyte right coronary artery gastric mucosa smooth muscle tissue upper lobe of left lung skin of hip Top expressed in renal corpuscle

Primary-amine oxidase (878 words) [view diff] exact match in snippet view article find links to article

inhibitors and stronger inhibitors have been developed. SSAO is found in the smooth muscle of blood vessels and various other tissues. The physiological function

DDR1 (1,214 words) [view diff] exact match in snippet view article find links to article

development regulation of extracellular matrix disassembly smooth muscle cell migration smooth muscle cell-matrix adhesion regulation of cell-matrix adhesion

AP3M1 (860 words) [view diff] exact match in snippet view article find links to article

mucosa of ileum ganglionic eminence ventricular zone islet of Langerhans smooth muscle tissue rectum tibialis anterior muscle monocyte appendix Top expressed

PPP1R12A (1,081 words) [view diff] exact match in snippet view article find links to article

light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine

Transforming growth factor, beta 3 (1,815 words) [view diff] exact match in snippet view article find links to article

saphenous vein canal of the cervix gallbladder prostate cartilage tissue smooth muscle tissue body of pancreas periodontal fiber body of uterus C1 segment

GPR34 (707 words) [view diff] exact match in snippet view article find links to article

pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon smooth muscle tissue testicle placenta mucosa of ileum right coronary artery appendix

GPR128 (529 words) [view diff] exact match in snippet view article find links to article

right lobe of liver mucosa of transverse colon gonad rectum gallbladder smooth muscle tissue appendix Top expressed in jejunum ileum colon duodenum spermatid

COPA (gene) (1,245 words) [view diff] exact match in snippet view article

anterior pituitary inferior ganglion of vagus nerve corpus callosum smooth muscle tissue pylorus cardia Top expressed in calvaria molar ascending aorta

GMP synthase (1,275 words) [view diff] exact match in snippet view article find links to article

eminence stromal cell of endometrium Achilles tendon islet of Langerhans smooth muscle tissue body of pancreas epithelium of colon Top expressed in otic vesicle

EGLN1 (3,422 words) [view diff] exact match in snippet view article find links to article

40-kd protein whose expression in the arterial wall is restricted to smooth muscle". Laboratory Investigation; A Journal of Technical Methods and Pathology

RhoC (1,931 words) [view diff] exact match in snippet view article find links to article

Descending thoracic aorta tibial nerve right coronary artery myometrium smooth muscle tissue left coronary artery Top expressed in decidua gastrula left colon

Cruzipain (1,052 words) [view diff] exact match in snippet view article find links to article

interacts with these immunoglobulins by cleaving their hinges. During smooth muscle cell invasion, cruzipain may mobilize vasoconstricting endothelin receptors

Collagen, type V, alpha 2 (1,121 words) [view diff] exact match in snippet view article find links to article

tibia cartilage tissue visceral pleura parietal pleura synovial joint smooth muscle tissue Top expressed in calvaria body of femur fossa stroma of bone

Thromboxane receptor (5,683 words) [view diff] exact match in snippet view article find links to article

contract diverse types of smooth muscle-containing tissues such as those of the lung, intestines, and uterus. TP contracts smooth muscle and stimulates various

GPR50 (786 words) [view diff] exact match in snippet view article find links to article

pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary smooth muscle tissue placenta hypothalamus ganglionic eminence lymph node islet of

COPB2 (1,161 words) [view diff] exact match in snippet view article find links to article

body of pancreas mucosa of sigmoid colon bronchial epithelial cell smooth muscle tissue Achilles tendon rectum Top expressed in ascending aorta aortic

GNGT2 (718 words) [view diff] exact match in snippet view article find links to article

monocyte spleen lymph node blood appendix mucosa of transverse colon smooth muscle tissue right lung gallbladder Top expressed in neural layer of retina

Terodiline (114 words) [view diff] exact match in snippet view article find links to article

Terodiline is a drug used in urology as an antispasmodic. It relaxes the smooth muscle and used to reduce bladder tone in treatment of urinary frequency and

SAE1 (1,477 words) [view diff] exact match in snippet view article find links to article

endometrium left testis right testis gonad oocyte prefrontal cortex smooth muscle tissue Top expressed in ventricular zone epiblast primitive streak somite

Alpha-enolase (1,935 words) [view diff] exact match in snippet view article find links to article

frontal lobe Achilles tendon renal medulla putamen mucosa of esophagus smooth muscle tissue embryo ascending aorta Top expressed in layer of retina neural

KCNK6 (727 words) [view diff] exact match in snippet view article find links to article

artery ascending aorta myometrium mucosa of transverse colon vagina smooth muscle tissue parotid gland Top expressed in fossa skin of abdomen right lobe

Ablomin (451 words) [view diff] exact match in snippet view article find links to article

contraction of arterial smooth muscle in rat-tails in a concentration-dependent matter. Reduction of arterial smooth muscle contraction in a rat-tail

KCND1 (587 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel

KCNMB4 (626 words) [view diff] exact match in snippet view article find links to article

calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits:

KCNH5 (550 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium

Manual lymphatic drainage (504 words) [view diff] exact match in snippet view article find links to article

the heart. The lymph system depends on intrinsic contractions of the smooth muscle cells in the walls of lymph vessels (peristalsis) and the movement of

Cartilage oligomeric matrix protein (1,350 words) [view diff] exact match in snippet view article find links to article

multicellular organism aging regulation of gene expression vascular associated smooth muscle contraction protein processing collagen fibril organization bone mineralization

Angina (5,871 words) [view diff] exact match in snippet view article find links to article

Propranolol and Nadolol, act on B1 receptors on smooth muscle cells as well. B1 blockade occurs in the smooth muscle cells. Specifically cAMP is responsible for

KCNMB3 (829 words) [view diff] exact match in snippet view article find links to article

calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits:

Interleukin 5 (1,529 words) [view diff] exact match in snippet view article find links to article

testis left testis Achilles tendon right uterine tube corpus callosum smooth muscle tissue granulocyte right ovary right coronary artery metanephros Top

Galanin receptor 2 (620 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in muscle layer of sigmoid colon transverse colon smooth muscle tissue granulocyte monocyte bone marrow hypothalamus small intestine

Ochnaflavone (450 words) [view diff] exact match in snippet view article find links to article

infection of the vascular smooth muscle cells. Find molecules that possess anti-proliferation activity of vascular smooth muscle cells seems a good strategy

KCNH5 (550 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium

Angina (5,871 words) [view diff] exact match in snippet view article find links to article

Propranolol and Nadolol, act on B1 receptors on smooth muscle cells as well. B1 blockade occurs in the smooth muscle cells. Specifically cAMP is responsible for

UBE2V1 (921 words) [view diff] exact match in snippet view article find links to article

Top expressed in epithelium of colon superior frontal gyrus tonsil smooth muscle tissue placenta ganglionic eminence primary visual cortex bone marrow

Elastic fiber (1,429 words) [view diff] exact match in snippet view article find links to article

number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. These fibers are able to stretch many

MYL9 (523 words) [view diff] exact match in snippet view article find links to article

1989). "Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells". Biochemistry. 28 (9):

ADAMTS4 (1,627 words) [view diff] exact match in snippet view article find links to article

stromal cell of endometrium right ovary C1 segment right auricle of heart smooth muscle tissue tibial nerve Top expressed in lumbar subsegment of spinal cord

TAS2R38 (2,405 words) [view diff] exact match in snippet view article find links to article

expressed in many tissues, such as human sinonasal epithelial cells, airway smooth muscle, monocytes, macrophages, heart, arteries, thyroid, skin, etc. Differential

TPM4 (639 words) [view diff] exact match in snippet view article find links to article

artery gallbladder ascending aorta body of uterus left uterine tube smooth muscle tissue Descending thoracic aorta tibial arteries Top expressed in genital

Endothelin receptor type B (1,733 words) [view diff] exact match in snippet view article find links to article

endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells]". Japanese Circulation Journal. 56 (Suppl 5): 1303–7. doi:10

Aphrodisiac (2,928 words) [view diff] exact match in snippet view article find links to article

increase sexual desire and sexual pleasure. Aphrodisiacs that have smooth muscle relaxing properties, such as yohimbine, have physiological effects that

Fibroblast growth factor 2 (2,730 words) [view diff] exact match in snippet view article find links to article

expressed in cartilage tissue Epithelium of choroid plexus Achilles tendon smooth muscle tissue stromal cell of endometrium Descending thoracic aorta adipose

KCNE4 (1,987 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNE4 gene encodes KCNE4 (originally

Julie Campbell (vascular biologist) (1,464 words) [view diff] exact match in snippet view article

AO FAA is an Australian vascular biologist specialising in vascular smooth muscle. She is a professional fellow at the Australian Academy of Science and

IGFBP4 (1,224 words) [view diff] exact match in snippet view article find links to article

liver right lobe of thyroid gland canal of the cervix body of uterus smooth muscle tissue Top expressed in external carotid artery internal carotid artery

Calponin 2 (2,194 words) [view diff] exact match in snippet view article find links to article

cell types, including developing and remodeling smooth muscle as well as adult mature smooth muscle, epidermal keratinocytes, fibroblasts, lung alveolar

Pancreatic polypeptide receptor 1 (1,020 words) [view diff] exact match in snippet view article find links to article

colon muscle layer of sigmoid colon duodenum mucosa of transverse colon smooth muscle tissue skin of abdomen skin of leg appendix stomach Top expressed in

F2RL2 (902 words) [view diff] exact match in snippet view article find links to article

gallbladder islet of Langerhans testicle skin of hip gastric mucosa smooth muscle tissue nipple Top expressed in lumbar spinal ganglion right lobe of

NT5E (2,272 words) [view diff] exact match in snippet view article find links to article

endometrium Achilles tendon jejunal mucosa synovial joint cartilage tissue smooth muscle tissue canal of the cervix tendon of biceps brachii germinal epithelium

Relaxin/insulin-like family peptide receptor 2 (791 words) [view diff] exact match in snippet view article find links to article

expressed in testicle monocyte granulocyte gonad left uterine tube blood smooth muscle tissue right adrenal cortex left adrenal gland left adrenal cortex Top

Alison Brading (853 words) [view diff] exact match in snippet view article find links to article

a British scientist who studied the physiology and pharmacology of smooth muscle, particularly in the urinary tract. Alison Brading was born in Bexhill-on-Sea

ASAH2 (687 words) [view diff] exact match in snippet view article find links to article

duodenum gonad testicle stromal cell of endometrium islet of Langerhans smooth muscle tissue ganglionic eminence muscle of thigh tonsil skeletal muscle tissue

PDCD1LG2 (2,216 words) [view diff] exact match in snippet view article find links to article

endometrium testicle Achilles tendon appendix lymph node spleen gallbladder smooth muscle tissue upper lobe of left lung right lung Top expressed in gastrula

Cytochalasin D (189 words) [view diff] exact match in snippet view article find links to article

1996). "Cytochalasin D inhibits smooth muscle contraction by directly inhibiting contractile apparatus". J Smooth Muscle Res. 32 (2): 51–60 – via PubMed

EIF6 (1,813 words) [view diff] exact match in snippet view article find links to article

colon skin of leg skin of abdomen duodenum rectum vagina human kidney smooth muscle tissue right lobe of liver Top expressed in epiblast primitive streak

Prolactin-releasing peptide receptor (986 words) [view diff] exact match in snippet view article find links to article

substantia nigra prefrontal cortex body of uterus vagina myometrium smooth muscle tissue Top expressed in hypothalamus cerebellum cerebellar cortex striatum

HAS2 (1,226 words) [view diff] exact match in snippet view article find links to article

"Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins". Circulation Research. 94 (5):

Nitric oxide synthase (3,612 words) [view diff] exact match in snippet view article find links to article

relaxing smooth muscle in their linings. eNOS is the primary controller of smooth muscle tone. NO activates guanylate cyclase, which induces smooth muscle relaxation

Prostaglandin F receptor (3,509 words) [view diff] exact match in snippet view article find links to article

expressed in the uterine myometrium; throughout the eye (endothelium and smooth muscle cells of blood vessels of the iris), ciliary body and choroid plexus;

Leukotriene (1,895 words) [view diff] exact match in snippet view article find links to article

double bonds). What would be later named leukotriene C, "slow reaction smooth muscle-stimulating substance" (SRS) was originally described between 1938 and

Cathepsin B (1,495 words) [view diff] exact match in snippet view article find links to article

of thyroid gland appendix canal of the cervix gallbladder ectocervix smooth muscle tissue olfactory zone of nasal mucosa monocyte Top expressed in stroma

Anatomical terminology (4,587 words) [view diff] no match in snippet view article find links to article

Anatomical terminology is a specialized system of terms used by anatomists, zoologists, and health professionals, such as doctors, surgeons, and pharmacists

Collagen, type VIII, alpha 1 (763 words) [view diff] exact match in snippet view article find links to article

expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes". J.

Physalaemin (546 words) [view diff] exact match in snippet view article find links to article

Researchers can make use of this behavior of PHY to study the behavior of smooth muscle - a tissue where NK1 can be found. Shiina et al. (2010) used PHY to

Calcium channel (768 words) [view diff] exact match in snippet view article find links to article

permeability has little effect on action potentials. However, in many smooth muscle tissues, depolarization is mediated primarily by calcium influx into

PLRG1 (693 words) [view diff] exact match in snippet view article find links to article

Top expressed in secondary oocyte Achilles tendon islet of Langerhans smooth muscle tissue body of uterus left lobe of thyroid gland palpebral conjunctiva

P2RY6 (1,079 words) [view diff] exact match in snippet view article find links to article

Granström G, Linde A (Feb 2002). "UDP acts as a growth factor for vascular smooth muscle cells by activation of P2Y6 receptors". Am J Physiol Heart Circ Physiol

Alpha-1A adrenergic receptor (1,360 words) [view diff] exact match in snippet view article find links to article

Wetzel JM, et al. (1994). "The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of

TLL1 (639 words) [view diff] exact match in snippet view article find links to article

of colon right hemisphere of cerebellum Achilles tendon gallbladder smooth muscle tissue Top expressed in muscular part of interventricular septum cardiac

Thrombospondin 1 (2,334 words) [view diff] exact match in snippet view article find links to article

pericardium gallbladder left uterine tube Achilles tendon right lung smooth muscle tissue upper lobe of left lung vena cava Top expressed in stroma of

Hypoxic pulmonary vasoconstriction (961 words) [view diff] exact match in snippet view article find links to article

hypoxia-sensitive voltage-gated potassium channels in pulmonary artery smooth muscle cells leading to depolarization. This depolarization activates voltage-dependent

CCL7 (2,555 words) [view diff] exact match in snippet view article find links to article

many types of cells, including stromal cells, keratinocytes, airway smooth muscle cells, parenchymal cells, fibroblasts and leukocytes and also in tumor

HMGN4 (333 words) [view diff] exact match in snippet view article find links to article

endothelial cell granulocyte superficial temporal artery endometrium smooth muscle tissue n/a More reference expression data BioGPS n/a Orthologs Species

Calcium signaling (2,484 words) [view diff] exact match in snippet view article find links to article

This leads to the actual contraction of the muscle. Contractions of smooth muscle fiber are dependent on how a Ca2+ influx occurs. When a Ca2+ influx

HDAC8 (1,546 words) [view diff] exact match in snippet view article find links to article

notably to acute myeloid leukemia and is related to actin cytoskeleton in smooth muscle cells. siRNA targeting HDAC8 showed anticancer effects. Inhibition of

GDF6 (1,170 words) [view diff] exact match in snippet view article find links to article

auricle of heart gastric mucosa right coronary artery Achilles tendon smooth muscle tissue left coronary artery Top expressed in auditory ossicle stapes

TOX4 (379 words) [view diff] exact match in snippet view article find links to article

cell of endometrium gastrocnemius muscle bone marrow cell beta cell smooth muscle tissue muscle of thigh monocyte tonsil Top expressed in spermatocyte

KLF17 (271 words) [view diff] exact match in snippet view article find links to article

Mouse (ortholog) Top expressed in left testis testicle right testis smooth muscle tissue gonad sperm stromal cell of endometrium right lung left adrenal

ZNF35 (214 words) [view diff] exact match in snippet view article find links to article

callosum tonsil islet of Langerhans ganglionic eminence bone marrow cell smooth muscle tissue skeletal muscle tissue stromal cell of endometrium Top expressed

Ectodysplasin A2 receptor (525 words) [view diff] exact match in snippet view article find links to article

right uterine tube Descending thoracic aorta ascending aorta testicle smooth muscle tissue left adrenal gland canal of the cervix left adrenal cortex Top

ATC code C02 (416 words) [view diff] no match in snippet view article find links to article

ATC code C02 Antihypertensives is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed

SOD2 (3,227 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell apoptotic process positive

Uterine fibroid (7,093 words) [view diff] exact match in snippet view article find links to article

also known as uterine leiomyomas, fibromyoma or fibroids, are benign smooth muscle tumors of the uterus, part of the female reproductive system. Most people

RHEB (2,680 words) [view diff] exact match in snippet view article find links to article

Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence smooth muscle tissue Brodmann area 9 gastric mucosa cingulate gyrus anterior cingulate

Dedicator of cytokinesis protein 5 (562 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle contraction positive regulation of vascular associated smooth muscle cell migration positive regulation

MEF2C (1,895 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation

GDF3 (900 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in gonad testicle spleen muscle tissue lymph node smooth muscle tissue right adrenal gland adrenal cortex left adrenal cortex right

PDIA3 (1,282 words) [view diff] exact match in snippet view article find links to article

lobe of thyroid gland right lobe of thyroid gland anterior pituitary smooth muscle tissue mucosa of sigmoid colon rectum Top expressed in seminal vesicula

SULF2 (483 words) [view diff] exact match in snippet view article find links to article

ovary ectocervix left uterine tube monocyte tendon of biceps brachii smooth muscle tissue Top expressed in tail of embryo calvaria genital tubercle fossa

Nicorandil (869 words) [view diff] exact match in snippet view article find links to article

myosin phosphatase activity, decreasing the calcium sensitivity of the smooth muscle. PKG also activates the sarcolemma calcium pump to remove activating

KCNAB1 (985 words) [view diff] exact match in snippet view article find links to article

secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel

Neuropilin 1 (1,812 words) [view diff] exact match in snippet view article find links to article

epithelium of colon gallbladder left ventricle subcutaneous adipose tissue smooth muscle tissue Top expressed in internal carotid artery external carotid artery

CXCL10 (1,311 words) [view diff] exact match in snippet view article find links to article

lymph node rectum monocyte granulocyte olfactory zone of nasal mucosa smooth muscle tissue epithelium of nasopharynx Top expressed in mesenteric lymph nodes

CD59 (1,653 words) [view diff] exact match in snippet view article find links to article

gallbladder upper lobe of left lung minor salivary glands tibial nerve smooth muscle tissue spinal ganglia Top expressed in brown adipose tissue spermatid

Alpha-1B adrenergic receptor (1,333 words) [view diff] exact match in snippet view article find links to article

Wetzel JM, et al. (1994). "The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of

PARVA (680 words) [view diff] exact match in snippet view article find links to article

RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in smooth muscle tissue stromal cell of endometrium epithelium of colon myometrium muscle

Zinc transporter ZIP12 (2,884 words) [view diff] exact match in snippet view article find links to article

ZIP12 results in the proliferation and thickening of pulmonary vascular smooth muscle cells, which leads to pulmonary hypertension. Zhao et al. identified

Neuropeptide S receptor (1,565 words) [view diff] exact match in snippet view article find links to article

gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. This gene is a member of the G protein-coupled

Lumbar ganglia (764 words) [view diff] exact match in snippet view article find links to article

vessels, and stimulating the secretion of acetylcholine, which causes smooth muscle contraction that leads to an increase in heart rate, blood sugar level

CLIC4 (1,251 words) [view diff] exact match in snippet view article find links to article

popliteal artery tibial arteries vena cava Descending thoracic aorta smooth muscle tissue ascending aorta right coronary artery urethra Top expressed in

Lymphangion (309 words) [view diff] exact match in snippet view article find links to article

lymphangion. Pressure in the first lymphangion may increase because of smooth muscle contraction (in lymph vessel) or because of pressure on the walls from

Sonic hedgehog protein (7,477 words) [view diff] exact match in snippet view article find links to article

guidance negative regulation of ureter smooth muscle cell differentiation positive regulation of ureter smooth muscle cell differentiation multicellular organism

Rho kinase inhibitor (1,646 words) [view diff] exact match in snippet view article find links to article

cellular level, ROCK has multiple functions, including regulation of smooth muscle cell contraction, cell migration, and maintenance of cell viability

CRIP2 (567 words) [view diff] exact match in snippet view article find links to article

act to bridge serum response factor and GATA proteins and stimulate smooth muscle target genes. GRCh38: Ensembl release 89: ENSG00000182809 – Ensembl

Keratin 20 (1,190 words) [view diff] exact match in snippet view article find links to article

transverse colon rectum duodenum appendix epithelium of colon gastric mucosa smooth muscle tissue body of stomach urinary bladder muscle layer of sigmoid colon

Lamina propria (1,298 words) [view diff] exact match in snippet view article find links to article

both smooth muscle and fibroblasts. The lamina propria may also be rich in vascular networks, lymphatic vessels, elastic fibers, and smooth muscle fascicles

DNMT1 (2,631 words) [view diff] exact match in snippet view article find links to article

regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell apoptotic process negative

Fibroblastic and myofibroblastic tumors (2,397 words) [view diff] exact match in snippet view article find links to article

cytoplasm and more prominent nucleoli; they express smooth muscle marker proteins such as smooth muscle actins, desmin, and caldesmon. The World Health Organization

Succinate dehydrogenase complex subunit C (2,174 words) [view diff] exact match in snippet view article find links to article

adrenal cortex human kidney left adrenal gland left adrenal cortex rectum smooth muscle tissue duodenum left ventricle right lobe of liver Top expressed in

Plasminogen activator inhibitor-1 (1,603 words) [view diff] exact match in snippet view article find links to article

regulation of plasminogen activation fibrinolysis negative regulation of smooth muscle cell-matrix adhesion negative regulation of blood coagulation negative

SLC2A7 (255 words) [view diff] exact match in snippet view article find links to article

pattern Bgee Human Mouse (ortholog) Top expressed in duodenum colon smooth muscle tissue Top expressed in jejunum duodenum blastocyst yolk sac embryo

Zinc transporter ZIP3 (359 words) [view diff] exact match in snippet view article find links to article

of endometrium prefrontal cortex apex of heart islet of Langerhans smooth muscle tissue Brodmann area 9 monocyte cingulate gyrus Top expressed in neural

POU4F3 (561 words) [view diff] exact match in snippet view article find links to article

RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in smooth muscle tissue tibial arteries islet of Langerhans C1 segment Top expressed

NKX3-2 (660 words) [view diff] exact match in snippet view article find links to article

cartilage tissue tendon of biceps brachii transverse colon gonad spleen smooth muscle tissue embryo rectum Top expressed in sclerotome female urethra male

PPP1R14A (1,266 words) [view diff] exact match in snippet view article find links to article

PPP1R14A gene. CPI-17 is a phosphorylation-dependent inhibitor protein of smooth muscle myosin phosphatase, discovered in pig aortic homogenates. Phosphorylation

Interleukin 20 (1,396 words) [view diff] exact match in snippet view article find links to article

(ortholog) Top expressed in gonad pancreatic ductal cell seminal vesicula smooth muscle tissue stromal cell of endometrium olfactory zone of nasal mucosa left

ZNF259 (477 words) [view diff] exact match in snippet view article find links to article

Langerhans sural nerve Achilles tendon body of pancreas right lobe of liver smooth muscle tissue Top expressed in epiblast tail of embryo embryo Rostral migratory

NOV (gene) (1,878 words) [view diff] exact match in snippet view article

2010). "CCN3 inhibits neointimal hyperplasia through modulation of smooth muscle cell growth and migration". Arteriosclerosis, Thrombosis, and Vascular

Kininogen (1,648 words) [view diff] exact match in snippet view article find links to article

biologically active polypeptides involved in blood coagulation, vasodilation, smooth muscle contraction, inflammatory regulation, and the regulation of the cardiovascular

ZNF239 (508 words) [view diff] exact match in snippet view article find links to article

pancreas islet of Langerhans stromal cell of endometrium prefrontal cortex smooth muscle tissue Top expressed in Ileal epithelium cingulate gyrus CA3 field superior

KLF14 (572 words) [view diff] exact match in snippet view article find links to article

gastrocnemius muscle subcutaneous adipose tissue skeletal muscle tissue smooth muscle tissue Top expressed in pituitary gland yolk sac lumbar subsegment of