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searching for Ku70 32 found (71 total)

alternate case: ku70

Granzyme A (1,633 words) [view diff] exact match in snippet view article find links to article

Granzyme B. Substrates of GzmA include Pro-IL-1β, NDUFS3, SET, APE1, and Ku70 among others. In vitro studies suggest that GzmA may have less cytotoxic

Clusterin (2,321 words) [view diff] exact match in snippet view article find links to article

survival and resistance to apoptosis. It facilitates the binding of BAX to Ku70, thereby preventing BAX from localizing to the outer mitochondrial membrane

Rocky Mountain spotted fever (4,403 words) [view diff] exact match in snippet view article find links to article

protein called Ku70. It has previously been reported that Ku70 migrates to the host cell surface in the presence of "Rickettsia". Then, Ku70 is ubiquitinated

Ketan J. Patel (1,499 words) [view diff] exact match in snippet view article find links to article

Hodskinson, M. R.; Rosado, I. V.; Sivasubramaniam, M; Patel, K. J. (2010). "Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway". Science

Sirtuin (2,085 words) [view diff] exact match in snippet view article find links to article

H3K9ac, H1K26ac, H4K16ac Hif-1α, Hif-2α, MYC, P53, BRCA1, FOXO3A, MyoD, Ku70, PPARγ, PCAF, Suv39h1, TGFB1, WRN, NBS1 Neurodegenerative diseases, Cancer:

Adenovirus early region 1A (2,233 words) [view diff] exact match in snippet view article find links to article

binding of RubBL1 repressing gene activation induced by interferons, and Ku70 being an inhibitor of DNA response to damage. Additionally, mutations observed

Homology directed repair (1,265 words) [view diff] exact match in snippet view article find links to article

been initiated instead of NHEJ. In contrast, the presence of a Ku complex (Ku70 and Ku80) indicates that NHEJ has been initiated instead of HDR. HDR and

Genetics of aging (2,852 words) [view diff] exact match in snippet view article find links to article

unclear, but the human SIRT1 protein has been demonstrated to deacetylate p53, Ku70, and the forkhead family of transcription factors. SIRT1 can also regulate

List of airports by IATA airport code: I (245 words) [view diff] case mismatch in snippet view article find links to article

Sicogon Airport Sicogon, Philippines UTC+08:00 ICS Cascade Airport (FAA: KU70) Cascade, Idaho, United States UTC−07:00 Mar-Nov ICT KICT Wichita Dwight

Isogenic human disease models (2,046 words) [view diff] exact match in snippet view article find links to article

PMID 18559665. Fattah FJ, Lichter NF, Fattah KR, Oh S, Hendrickson EA (June 2008). "Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting

SLC22A1 (1,255 words) [view diff] exact match in snippet view article find links to article

IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements". The Journal of Biological Chemistry

NEDD8 (2,836 words) [view diff] exact match in snippet view article find links to article

DNA double-strand breaks. The first step in this pathway depends on the Ku70/Ku80 heterodimer that forms a highly stable ring structure encircling DNA

APPBP1 (2,792 words) [view diff] exact match in snippet view article find links to article

DNA double-strand breaks. The first step in this pathway depends on the Ku70/Ku80 heterodimer that forms a highly stable ring structure encircling DNA

DNA-PKcs (3,820 words) [view diff] exact match in snippet view article find links to article

Queseth S, Fornander T, Askmalm MS (December 2010). "Low expression of Ku70/80, but high expression of DNA-PKcs, predict good response to radiotherapy

Simon Boulton (1,928 words) [view diff] exact match in snippet view article find links to article

PMID 8972848. Boulton, S. J.; Jackson, S. P. (1996). "Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier

Rad50 (2,219 words) [view diff] exact match in snippet view article find links to article

Goedecke W, Eijpe M, Offenberg HH, van Aalderen M, Heyting C (1999). "Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis"

Regulatory sequence (4,306 words) [view diff] case mismatch in snippet view article find links to article

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80 and DNA LIGASE IV) (see figure). These enzymes repair the double-strand

DNA repair (16,295 words) [view diff] case mismatch in snippet view article find links to article

by enabling the recruitment of essential repair factors, including RAD51, KU70, and KU80, to double-strand breaks. Such chromatin-based mechanisms illustrate

TOP2B (2,299 words) [view diff] case mismatch in snippet view article find links to article

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80 and DNA LIGASE IV) (see Figure). These enzymes repair the double-strand

Aedes aegypti (5,078 words) [view diff] exact match in snippet view article find links to article

Kmo (kynurenine 3-monoxygenase), loqs (loquacious), r2d2 (r2d2 protein), ku70 (ku heterodimer protein gene) and lig4 (ligase4) were targeted to modify

FOXL2 (2,264 words) [view diff] case mismatch in snippet view article find links to article

(RINF/WID), CREM, GMEB1 (P96PIF), NR2C1 (TR2), SP100, RPLP1, BAF (BANF1), XRCC6 (KU70) and SIRT1. FOXL2 is involved in sex determination. FOXL2 knockout in mature

TOP2B (2,299 words) [view diff] case mismatch in snippet view article find links to article

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80 and DNA LIGASE IV) (see Figure). These enzymes repair the double-strand

Recombinant AAV mediated genome engineering (2,697 words) [view diff] exact match in snippet view article find links to article

PMID 18559665. Fattah FJ, Lichter NF, Fattah KR, Oh S, Hendrickson EA (June 2008). "Ku70, an essential gene, modulates the frequency of rAAV-mediated gene targeting

POU2AF1 (1,485 words) [view diff] exact match in snippet view article find links to article

IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements". J. Biol. Chem. 278 (25): 23141–50

Memory (17,398 words) [view diff] case mismatch in snippet view article find links to article

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80, and DNA LIGASE IV) (see Figure). These enzymes repair the double-strand

Myocardin (1,531 words) [view diff] exact match in snippet view article find links to article

et al. (July 2021). "SAP domain forms a flexible part of DNA aperture in Ku70/80". The FEBS Journal. 288 (14): 4382–4393. doi:10.1111/febs.15732. PMC 8653891

Custirsen (1,236 words) [view diff] exact match in snippet view article find links to article

complexes. These include: The binding of clusterin to a structurally altered Ku70–Bax complex Regulation of Nuclear Factor (NF)-κB activity and signalling

Epigenetics in learning and memory (6,247 words) [view diff] case mismatch in snippet view article find links to article

enzymes of the non-homologous end joining (NHEJ) DNA repair pathway (DNA-PKcs, KU70, KU80 and DNA LIGASE IV) (see Figure). These enzymes repair the double-strand

Haim Cohen (1,364 words) [view diff] exact match in snippet view article find links to article

In the first, Cohen showed, for the first time, how the repair protein Ku70 controls cell death through its action as deubiquitinase. This finding is

Nuclear mitochondrial DNA segment (6,838 words) [view diff] exact match in snippet view article find links to article

required to facilitate the occurrence of the indicated events. In NHEJ, the Ku70/Ku80 heterodimer and DNA-dependent protein kinase (DNA-PK) for bringing DNA

List of minor planets: 165001–166000 (294 words) [view diff] case mismatch in snippet view article find links to article

KT65 — May 27, 2000 Anderson Mesa LONEOS · 4.8 km MPC · JPL 165135 2000 KU70 — May 28, 2000 Socorro LINEAR · 6.5 km MPC · JPL 165136 2000 KN74 — May

List of minor planets: 819001–820000 (294 words) [view diff] case mismatch in snippet view article find links to article

819623 2014 KH70 — May 23, 2014 Haleakala Pan-STARRS · MPC · JPL 819624 2014 KU70 — May 23, 2014 Haleakala Pan-STARRS · MPC · JPL 819625 2014 KV71 — May 23