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searching for Kinetochore 160 found (259 total)

Centromere protein E (1,069 words) [view diff] exact match in snippet view article find links to article

Yen TJ (Mar 1995). "Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41,

CENPT (560 words) [view diff] exact match in snippet view article find links to article

nucleoplasm chromosome, centromeric region nucleus kinetochore nuclear body Biological process kinetochore assembly CENP-A containing chromatin assembly chromosome

DNA replication factor CDT1 (1,439 words) [view diff] exact match in snippet view article find links to article

nucleus nucleoplasm nuclear body chromosome, centromeric region chromosome kinetochore cytoplasm Biological process DNA replication checkpoint signaling DNA

NSL1 (646 words) [view diff] exact match in snippet view article find links to article

Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene. This gene encodes a protein with two coiled-coil

CENPK (451 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region chromosome kinetochore Biological process CENP-A containing chromatin assembly kinetochore assembly mitotic sister chromatid segregation

TTK (gene) (835 words) [view diff] exact match in snippet view article

Kinase Is Required for Mitotic Arrest Induced by the Loss of CENP-E from Kinetochores". Mol. Biol. Cell. 14 (4): 1638–51. doi:10.1091/mbc.02-05-0074. PMC 153128

NUF2 (945 words) [view diff] exact match in snippet view article find links to article

Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene. This gene encodes a protein that is highly similar to yeast Nuf2, a

CENPL (2,536 words) [view diff] exact match in snippet view article find links to article

known for its role in forming the centromere and building a functional kinetochore during cell division. CENPL acts as part of the CENP-L/N complex and

MIS12 (649 words) [view diff] exact match in snippet view article find links to article

200210005. PMC 2172742. PMID 12515822. "Entrez Gene: MIS12 MIS12, MIND kinetochore complex component, homolog (yeast)". Obuse, Chikashi; Iwasaki Osamu;

SPC24 (370 words) [view diff] exact match in snippet view article find links to article

Kinetochore protein Spc24 is a protein that in humans is encoded by the SPC24 gene. GRCh38: Ensembl release 89: ENSG00000161888 – Ensembl, May 2017 GRCm38:

Dynactin (2,819 words) [view diff] exact match in snippet view article find links to article

(Plk1) to kinetochores through cyclin dependent kinase 1 (Cdk1)-phosphorylated DCTN6/p27, which is involved in proper microtubule-kinetochore attachment

KIF2C (979 words) [view diff] exact match in snippet view article find links to article

CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes". Human Molecular Genetics. 9 (19): 2919–2926. doi:10.1093/hmg/9

2700099C18Rik (37 words) [view diff] exact match in snippet view article find links to article

homolog, kinetochore complex component pseudogene is a mouse pseudogene with symbol 2700099C18Rik. "Entrez Gene: NDC80 homolog, kinetochore complex component

CLASP2 (691 words) [view diff] exact match in snippet view article find links to article

Maiato H, Fairley EA, Rieder CL, et al. (2003). "Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics". Cell. 113 (7):

Nuclear pore complex protein Nup133 (901 words) [view diff] exact match in snippet view article find links to article

stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. NUP133 has been shown to interact with NUP107. GRCh38:

Polyamine-modulated factor 1 (470 words) [view diff] exact match in snippet view article find links to article

(September 2004). "A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension". Genes & Development. 18 (18): 2255–68

KIF18A (869 words) [view diff] exact match in snippet view article find links to article

ATPase activity Cellular component cytoplasm cytosol cell projection kinetochore microtubule kinesin complex ruffle microtubule cytoskeleton microtubule

DYNC1LI1 (456 words) [view diff] exact match in snippet view article find links to article

dynein complex microtubule chromosome, centromeric region cytoskeleton kinetochore cytoplasm cytosol plasma membrane secretory granule membrane ficolin-1-rich

DYNC1LI2 (432 words) [view diff] exact match in snippet view article find links to article

membrane dynein complex microtubule cytoskeleton cytoplasmic dynein complex kinetochore lysosome late endosome centrosome Biological process antigen processing

Nucleoporin 160 (671 words) [view diff] exact match in snippet view article find links to article

evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb

CHAMP1 (1,139 words) [view diff] exact match in snippet view article find links to article

Kiyono T (January 2011). "CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment". The EMBO Journal. 30 (1): 130–44. doi:10.1038/emboj

Microtubule (7,913 words) [view diff] exact match in snippet view article find links to article

attach to the kinetochores can aid in chromosome congregation through lateral interaction with the kinetochores. K fibers/Kinetochore microtubules are

Nucleoporin 107 (1,259 words) [view diff] exact match in snippet view article find links to article

Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc

SUGT1 (558 words) [view diff] exact match in snippet view article find links to article

homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation

DYNC1I1 (737 words) [view diff] exact match in snippet view article find links to article

granule microtubule chromosome, centromeric region cytoskeleton nucleus kinetochore cytoplasmic dynein complex Biological process antigen processing and

NEK2 (1,182 words) [view diff] exact match in snippet view article find links to article

NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80

KIF22 (1,072 words) [view diff] exact match in snippet view article find links to article

kinesin complex spindle chromatin mitotic spindle microtubule cytoskeleton kinetochore nucleus cytoplasm cytosol nuclear speck Biological process metaphase

Nucleoporin 85 (627 words) [view diff] exact match in snippet view article find links to article

Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc

MAD1L1 (644 words) [view diff] exact match in snippet view article find links to article

reference expression data Gene ontology Molecular function protein binding kinetochore binding identical protein binding Cellular component centrosome spindle

CENPI (650 words) [view diff] exact match in snippet view article find links to article

2003). "Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis". Nature Cell Biology. 5 (4): 341–5. doi:10

CENPO (588 words) [view diff] exact match in snippet view article find links to article

Cellular component chromosome cytosol chromosome, centromeric region kinetochore nucleoplasm nucleus Mis6-Sim4 complex Biological process centromere complex

Kaustuv Sanyal (1,126 words) [view diff] exact match in snippet view article find links to article

Gordon Research Conference, EMBO conferences on comparative genomics and kinetochores. The Department of Biotechnology of the Government of India awarded him

Sperm-associated antigen 5 (582 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region microtubule plus-end midbody microtubule kinetochore cytoskeleton cytoplasm mitotic spindle pole spindle microtubule Biological

Shugoshin 2 (611 words) [view diff] exact match in snippet view article find links to article

Kitajima TS; Kawashima SA; Watanabe Y (February 2004). "The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis". Nature

Nucleoporin 43 (794 words) [view diff] exact match in snippet view article find links to article

Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Molecular Biology of the Cell. 15 (7): 3333–44. doi:10.1091/mbc

ZNF207 (84 words) [view diff] exact match in snippet view article find links to article

matrix microtubule chromosome, centromeric region cytoskeleton nucleus kinetochore nucleoplasm Biological process regulation of transcription, DNA-templated

KIAA0157 (399 words) [view diff] exact match in snippet view article find links to article

K63-linked deubiquitination cell cycle attachment of spindle microtubules to kinetochore protein deubiquitination mitotic cell cycle Sources:Amigo / QuickGO Orthologs

Anopheles gambiae (2,301 words) [view diff] exact match in snippet view article find links to article

gambiae codes for spindle and kinetochore-associated proteins. Hanisch et al., 2006 locate AgSka1, the spindle and kinetochore-associated protein 1 gene,

AHCTF1 (418 words) [view diff] exact match in snippet view article find links to article

Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division"

RCC2 (733 words) [view diff] exact match in snippet view article find links to article

passenger complex localization to kinetochore positive regulation of attachment of spindle microtubules to kinetochore focal adhesion assembly negative

Testis-expressed protein 14 (357 words) [view diff] exact match in snippet view article find links to article

centromeric region extracellular exosome intercellular bridge midbody kinetochore Biological process cell cycle negative regulation of cytokinesis cell

Adenomatous polyposis coli (3,227 words) [view diff] exact match in snippet view article find links to article

cell junction nucleus lamellipodium membrane Wnt signalosome centrosome kinetochore bicellular tight junction ruffle membrane plasma membrane lateral plasma

DYNLL1 (1,548 words) [view diff] exact match in snippet view article find links to article

mitotic spindle microtubule cytoskeleton extracellular exosome nucleus kinetochore cytoplasmic dynein complex cilium tertiary granule membrane ficolin-1-rich

Presenilin-2 (1,100 words) [view diff] exact match in snippet view article find links to article

membrane Z discdkac endoplasmic reticulum perinuclear region of cytoplasm kinetochore mitochondrial inner membrane lysosomal membrane cell cortex cell surface

ORC2 (1,480 words) [view diff] exact match in snippet view article find links to article

replication origin binding Cellular component heterochromatin inner kinetochore nuclear origin of replication recognition complex centrosome chromatin

SMC1A (2,092 words) [view diff] exact match in snippet view article find links to article

those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this

Survivin (780 words) [view diff] exact match in snippet view article find links to article

microtubule centriole cytoplasmic microtubule cytoskeleton microtubule kinetochore midbody cytoplasm chromosome, centromeric region nucleus Biological process

HNRPU (1,291 words) [view diff] exact match in snippet view article find links to article

regulator complex inactive sex chromosome ribonucleoprotein complex kinetochore centrosome midbody mitotic spindle mitotic spindle midzone mitotic spindle

SEC13 (807 words) [view diff] exact match in snippet view article find links to article

Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878

DCTN2 (1,058 words) [view diff] exact match in snippet view article find links to article

Goldberg ML (August 1998). "ZW10 helps recruit dynactin and dynein to the kinetochore". The Journal of Cell Biology. 142 (3): 763–74. doi:10.1083/jcb.142.3

PAFAH1B1 (1,513 words) [view diff] exact match in snippet view article find links to article

2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". The Journal of Cell Biology. 156 (6): 959–68. doi:10.1083/jcb

DCTN1 (1,632 words) [view diff] exact match in snippet view article find links to article

retromer complex cell leading edge dynein complex microtubule cytoskeleton kinetochore microtubule organizing center nucleus nuclear envelope centriole spindle

NUP98 (1,515 words) [view diff] exact match in snippet view article find links to article

outer ring nuclear inclusion body nuclear pore nuclear basket nucleus kinetochore nuclear pore cytoplasmic filaments nucleoplasm intracellular membrane-bounded

Tim J. Yen (555 words) [view diff] exact match in snippet view article find links to article

specific distribution), characterization of ATM, and identification of kinetochore assembly pathways. In 2001, Yen discovered the “mitotic checkpoint complex”

MAD2L1 (1,975 words) [view diff] exact match in snippet view article find links to article

(September 2002). "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". J. Cell Biol. 158 (5): 841–7. doi:10

SMC2 (1,317 words) [view diff] exact match in snippet view article find links to article

extracellular exosome condensed chromosome nucleus Biological process kinetochore organization meiotic chromosome condensation chromosome organization

NAS Award in Molecular Biology (1,796 words) [view diff] exact match in snippet view article find links to article

vitro characterization of a functional kinetochore complex, and for the use of that system to explore kinetochore function. 2014 David M. Sabatini for his

KAT8 regulatory NSL complex subunit 1 (719 words) [view diff] exact match in snippet view article find links to article

acetyltransferase complex MLL1 complex chromosome, centromeric region nucleus kinetochore chromosome nucleoplasm NSL complex Biological process histone H4-K16

SMC4 (1,454 words) [view diff] exact match in snippet view article find links to article

segregation meiotic chromosome segregation cell division cell cycle kinetochore organization mitotic chromosome condensation meiotic chromosome condensation

NDE1 (808 words) [view diff] exact match in snippet view article find links to article

cleavage furrow microtubule chromosome, centromeric region cytoskeleton kinetochore kinesin complex Biological process cell differentiation centrosome duplication

CBX5 (gene) (2,431 words) [view diff] exact match in snippet view article

Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nature Cell Biology. 6 (11): 1135–41. doi:10.1038/ncb1187

DCTN4 (346 words) [view diff] exact match in snippet view article find links to article

cytoskeleton nucleus dynactin complex microtubule organizing center kinetochore spindle pole stress fiber focal adhesion cell cortex sarcomere Biological

DCTN5 (280 words) [view diff] exact match in snippet view article find links to article

centrosome nuclear membrane chromosome, centromeric region cytoskeleton kinetochore nucleoplasm chromosome Biological process endoplasmic reticulum to Golgi

NUDCD2 (332 words) [view diff] exact match in snippet view article find links to article

intracellular anatomical structure chromosome, centromeric region cytoskeleton kinetochore chromosome microtubule organizing center cytoplasm Biological process

CFDP1 (591 words) [view diff] exact match in snippet view article find links to article

molecular function Cellular component chromosome, centromeric region kinetochore chromosome cellular component Biological process multicellular organism

SENP6 (789 words) [view diff] exact match in snippet view article find links to article

regulation of spindle assembly protein sumoylation proteolysis regulation of kinetochore assembly Sources:Amigo / QuickGO Orthologs Species Human Mouse Entrez

ITGB3BP (804 words) [view diff] exact match in snippet view article find links to article

membrane nucleoplasm chromosome chromosome, centromeric region nucleus kinetochore Biological process regulation of transcription, DNA-templated CENP-A

PHF6 (1,098 words) [view diff] exact match in snippet view article find links to article

Cellular component nucleolus chromosome, centromeric region nucleus kinetochore nucleoplasm chromosome Biological process regulation of transcription

MEAF6 (645 words) [view diff] exact match in snippet view article find links to article

complex histone acetyltransferase complex nucleus nucleolus chromosome kinetochore chromosome, centromeric region nucleoplasm NuA3a histone acetyltransferase

IK (gene) (304 words) [view diff] exact match in snippet view article

mitotic spindle assembly checkpoint signaling protein localization to kinetochore mRNA processing RNA splicing viral process mRNA splicing, via spliceosome

PHF2 (205 words) [view diff] exact match in snippet view article find links to article

component nucleoplasm chromosome nucleolus chromosome, centromeric region kinetochore nucleus Biological process regulation of transcription, DNA-templated

ECT2 (1,051 words) [view diff] exact match in snippet view article find links to article

signal transduction regulation of attachment of spindle microtubules to kinetochore regulation of small GTPase mediated signal transduction protein homooligomerization

Cytokinesis (3,616 words) [view diff] exact match in snippet view article find links to article

central spindle. The central spindle (or spindle midzone) forms when non-kinetochore microtubule fibers are bundled between the spindle poles. A number of

SUMO3 (983 words) [view diff] exact match in snippet view article find links to article

protein ligase binding Cellular component cytoplasm PML body nucleus kinetochore nucleoplasm Biological process negative regulation of DNA binding protein

SS18L1 (643 words) [view diff] exact match in snippet view article find links to article

Cellular component nBAF complex nuclear body chromosome, centromeric region kinetochore chromosome nucleus cytosol Biological process positive regulation of

RASSF2 (848 words) [view diff] exact match in snippet view article find links to article

Cellular component cytoplasm nucleus chromosome, centromeric region kinetochore chromosome nucleoplasm Golgi apparatus cytosol plasma membrane protein-containing

CLIP1 (1,099 words) [view diff] exact match in snippet view article find links to article

intermediate filament cytoplasmic vesicle membrane cytoplasmic vesicle kinetochore nuclear envelope cytoplasm Biological process microtubule bundle formation

PPP1CC (1,210 words) [view diff] exact match in snippet view article find links to article

mitochondrion cleavage furrow chromosome, centromeric region nucleus kinetochore protein phosphatase type 1 complex protein-containing complex presynapse

MLF1IP (748 words) [view diff] exact match in snippet view article find links to article

Park JE, Yu LR, et al. (2006). "Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation"

TP53BP1 (1,865 words) [view diff] exact match in snippet view article find links to article

cytoplasm nucleoplasm chromosome telomere chromosome, centromeric region kinetochore nuclear body nucleus replication fork site of double-strand break DNA

Securin (562 words) [view diff] exact match in snippet view article find links to article

Stegmeier F, Visintin R, Amon A (January 2002). "Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization

RAB11A (1,406 words) [view diff] exact match in snippet view article find links to article

mitochondrion multivesicular body trans-Golgi network Golgi apparatus cytosol kinetochore microtubule axon spindle pole membrane centrosome perinuclear region

POGZ (678 words) [view diff] exact match in snippet view article find links to article

nucleoplasm cytosol histone methyltransferase complex Biological process kinetochore assembly cell cycle mitotic sister chromatid cohesion cell division regulation

SIN3A (3,126 words) [view diff] exact match in snippet view article find links to article

transcription repressor complex nucleoplasm nucleolus chromatin nucleus kinetochore Sin3 complex protein-containing complex Biological process negative regulation

Apc, wnt signaling pathway regulator (617 words) [view diff] exact match in snippet view article find links to article

cell junction nucleus lamellipodium membrane Wnt signalosome centrosome kinetochore bicellular tight junction ruffle membrane plasma membrane lateral plasma

SEPT6 (1,133 words) [view diff] exact match in snippet view article find links to article

furrow chromosome, centromeric region cytoskeleton synaptic vesicle kinetochore chromosome septin ring septin collar septin complex sperm annulus cell

CDC42 (3,700 words) [view diff] exact match in snippet view article find links to article

kinase activity regulation of attachment of spindle microtubules to kinetochore regulation of small GTPase mediated signal transduction positive regulation

DNAI1 (798 words) [view diff] exact match in snippet view article find links to article

(2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". Journal of Cell Biology. 156 (6): 959–968. doi:10.1083/jcb

DCTN3 (581 words) [view diff] exact match in snippet view article find links to article

cytoplasm cleavage furrow chromosome, centromeric region cytoskeleton kinetochore nucleolus cytosol microtubule Biological process antigen processing and

NCAPG2 (410 words) [view diff] exact match in snippet view article find links to article

component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores". Nature Communications. 5: 4588. Bibcode:2014NatCo

SEPT2 (1,266 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region cytoskeleton extracellular exosome nucleus kinetochore cytosol sperm annulus non-motile cilium cilium septin ring microtubule

XPO1 (2,034 words) [view diff] exact match in snippet view article find links to article

membrane-bounded organelle nuclear envelope nucleoplasm lamellae anulatae nucleus kinetochore nucleolus cytosol host cell protein-containing complex ribonucleoprotein

SEPT7 (1,194 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region cytoskeleton extracellular exosome nucleus kinetochore cytoplasm sperm annulus non-motile cilium septin ring microtubule cytoskeleton

PCAF (2,222 words) [view diff] exact match in snippet view article find links to article

band nucleoplasm histone acetyltransferase complex A band actomyosin kinetochore nucleus cytoplasm centrosome microtubule organizing center cytoskeleton

PPP1R12A (1,081 words) [view diff] exact match in snippet view article find links to article

PTW/PP1 phosphatase complex actin cytoskeleton contractile fiber A band kinetochore cytoplasm cytosol cytoskeleton Biological process regulation of nucleocytoplasmic

40S ribosomal protein S27 (1,369 words) [view diff] exact match in snippet view article find links to article

Nigg EA (Sep 2002). "Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2". Science. 297 (5590): 2267–70. Bibcode:2002Sci

KAT8 (1,112 words) [view diff] exact match in snippet view article find links to article

nucleoplasm chromosome MLL1 complex histone acetyltransferase complex nucleus kinetochore MSL complex nuclear matrix Biological process myeloid cell differentiation

RANGAP1 (1,428 words) [view diff] exact match in snippet view article find links to article

Karpova TS, McNally JG, Dasso M (2002). "SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles". J. Cell Biol. 156 (4): 595–602. doi:10.1083/jcb

Jason Swedlow (1,318 words) [view diff] exact match in snippet view article find links to article

Swedlow, J. R. (2010). "Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis" (PDF). The Journal of Cell Biology. 191 (1):

KRP (biochemistry) (201 words) [view diff] exact match in snippet view article

a KRP that is involved in resolving errors during mitosis involving kinetochore-microtubules. This process is associated with Aurora B Protein Kinase

Cyclin-dependent kinase 1 (2,896 words) [view diff] exact match in snippet view article find links to article

peroxide cellular response to hydrogen peroxide protein localization to kinetochore apoptotic process cell population proliferation proteasome-mediated ubiquitin-dependent

Aurora kinase A (2,716 words) [view diff] exact match in snippet view article find links to article

during prometaphase. It is directly involved in the interaction of the kinetochore, the part of the chromosome at which the mitotic spindle attaches and

BECN1 (1,482 words) [view diff] exact match in snippet view article find links to article

positive regulation of attachment of mitotic spindle microtubules to kinetochore amyloid-beta metabolic process neuron development defense response to

Chromosome 17 (2,248 words) [view diff] exact match in snippet view article find links to article

protein 1 SEPTIN4: encoding Septin4 SKA2: encoding protein Spindle and Kinetochore Associated SLC39A11: encoding protein Solute carrier family 39 member

Cyclin B1 (3,282 words) [view diff] exact match in snippet view article find links to article

division positive regulation of attachment of spindle microtubules to kinetochore protein phosphorylation mitotic nuclear membrane disassembly cellular

Centromere protein B (1,175 words) [view diff] exact match in snippet view article find links to article

Ohndorf S, Benndorf K, et al. (January 2008). "Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells". ChemBioChem. 9 (1):

Presenilin-1 (3,111 words) [view diff] exact match in snippet view article find links to article

mitochondrion ciliary rootlet neuron projection gamma-secretase complex nucleus kinetochore centrosome rough endoplasmic reticulum dendritic shaft aggresome cell

Xenopus (5,879 words) [view diff] exact match in snippet view article find links to article

regulating spindle morphogenesis and to identify new proteins that mediate kinetochore attachment to microtubules. Cell-free systems have recently become practical

RACGAP1 (1,605 words) [view diff] exact match in snippet view article find links to article

proliferation cell cycle regulation of attachment of spindle microtubules to kinetochore regulation of small GTPase mediated signal transduction signal transduction

Separase (1,199 words) [view diff] exact match in snippet view article find links to article

Stegmeier F, Visintin R, Amon A (January 2002). "Separase, polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization

Heat shock factor protein 1 (2,458 words) [view diff] exact match in snippet view article find links to article

spindle pole ribonucleoprotein complex chromosome, centromeric region kinetochore spindle pole nucleoplasm chromosome microtubule organizing center cytoskeleton

Mary Dasso (1,133 words) [view diff] exact match in snippet view article find links to article

complex proteins, called nucleoporins, localize to mitotic spindles and kinetochores; this localization is essential for proper spindle assembly and cell

ERCC excision repair 6 like, spindle assembly checkpoint helicase (669 words) [view diff] exact match in snippet view article find links to article

component cytosol membrane chromosome chromosome, centromeric region kinetochore Biological process cell division cell cycle sister chromatid cohesion

Sirtuin 2 (3,241 words) [view diff] exact match in snippet view article find links to article

deacetylation positive regulation of attachment of spindle microtubules to kinetochore meiosis cellular response to caloric restriction ripoptosome assembly

INCENP (1,741 words) [view diff] exact match in snippet view article find links to article

synaptonemal complex chromosome, centromeric region microtubule cytoskeleton kinetochore nucleus cytosol nuclear body midbody protein-containing complex Biological

DYNC1H1 (1,901 words) [view diff] exact match in snippet view article find links to article

2002). "Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function". The Journal of Cell Biology. 156 (6): 959–968. doi:10.1083/jcb

CDC20 (3,307 words) [view diff] exact match in snippet view article find links to article

(September 2002). "Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells". J. Cell Biol. 158 (5): 841–7. doi:10

Hesperadin (221 words) [view diff] exact match in snippet view article find links to article

small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint"

David Glover (geneticist) (997 words) [view diff] exact match in snippet view article

the localisation and function of Polo kinase at the centrosome, the kinetochore and the central spindle in cytokinesis was highly conserved in human

Centrocone (299 words) [view diff] exact match in snippet view article find links to article

PMID 16684814. Farrell M, Gubbels MJ (January 2014). "The Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole)"

Casein kinase 1, alpha 1 (340 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region cytoskeleton beta-catenin destruction complex kinetochore nucleus cytosol cilium cell projection ciliary basal body ribonucleoprotein

Casein kinase 1, alpha 1 (340 words) [view diff] exact match in snippet view article find links to article

chromosome, centromeric region cytoskeleton beta-catenin destruction complex kinetochore nucleus cytosol cilium cell projection ciliary basal body ribonucleoprotein

Kinesin 13 (582 words) [view diff] exact match in snippet view article find links to article

chromatids, and this is accomplished in part during anaphase A when "kinetochore microtubules (or kMTs)" that link the sister chromatids to opposite spindle

Sally Hughes-Schrader (315 words) [view diff] exact match in snippet view article find links to article

Retrieved 14 July 2014. Hughes-Schrader, Sally (Dec 1943). "Polarization, Kinetochore Movements, and Bivalent Structure in the Meiosis of Male Mantids". The

RNF4 (2,192 words) [view diff] exact match in snippet view article find links to article

transcription, DNA-templated protein K11-linked ubiquitination regulation of kinetochore assembly protein K48-linked ubiquitination protein K6-linked ubiquitination

NDEL1 (2,011 words) [view diff] exact match in snippet view article find links to article

axon hillock microtubule chromosome, centromeric region cytoskeleton kinetochore axon cytoplasm cytosol central region of growth cone centrosome kinesin

MIS18A (575 words) [view diff] exact match in snippet view article find links to article

MIS18A, B28, C21orf45, C21orf46, FASP1, MIS18alpha, hMis18alpha, MIS18 kinetochore protein A External IDs OMIM: 618137; MGI: 1913828; HomoloGene: 41294;

ACTR1A (1,193 words) [view diff] exact match in snippet view article find links to article

neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins". Hum. Mol. Genet. 9 (2): 175–85. doi:10.1093/hmg/9

Carpediemonas (1,515 words) [view diff] exact match in snippet view article find links to article

subunits of polymerases delta and epsilon, as well as most structural kinetochore subunits, a microtubule plus-end tracking complex and all subunits of

Polo-like kinase (1,510 words) [view diff] exact match in snippet view article find links to article

cytokinesis, Plks associate with several structures including the centrosome, kinetochores, and the central spindle. The catalytic serine/threonine kinase domain

C8orf58 (609 words) [view diff] exact match in snippet view article find links to article

(Centromere Protein H) plays a critical role in centromere structure, kinetochore formation, and sister chromatid separation. MetG1 (Methionine—tRNA ligase)

Pseudoenzyme (1,389 words) [view diff] exact match in snippet view article find links to article

nucleating the CENP-I, CENP-H, CENP-K small GTPase complex to regulate kinetochore assembly Regulation of protein localisation in a cell Yeast light intermediate

Anaphase-promoting complex (4,194 words) [view diff] exact match in snippet view article find links to article

sister-kinetochores are attached to opposite poles of the mitotic spindle, a process known as chromosome biorientation. When all kinetochores are properly

Mosaic variegated aneuploidy syndrome (1,365 words) [view diff] exact match in snippet view article find links to article

McKeon, F. (1998-07-13). "The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase". The Journal

Karen Oegema (844 words) [view diff] exact match in snippet view article find links to article

identify and characterize multiple proteins involved in the regulation of kinetochores and their role in chromosome segregation, known now as CENP-AHCP-3, CENP-CHCP-4

Karyotype (7,025 words) [view diff] exact match in snippet view article find links to article

multiple names: authors list (link) Godfrey LR, Masters JC (August 2000). "Kinetochore reproduction theory may explain rapid chromosome evolution". Proc. Natl

Anton Schneider (356 words) [view diff] exact match in snippet view article find links to article

Rachel J.; Sullivan, Beth A. (2012). "Foreword: the centromere and kinetochore in creatures great and small". Chromosome Research. 20 (5): 461–463.

NUDC (1,087 words) [view diff] exact match in snippet view article find links to article

BR, Yu-Lee LY (Jul 2006). "NudC is required for Plk1 targeting to the kinetochore and chromosome congression". Current Biology. 16 (14): 1414–21. Bibcode:2006CBio

COPS7A (787 words) [view diff] exact match in snippet view article find links to article

Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1". Nat. Cell Biol. 6 (11): 1135–41. doi:10.1038/ncb1187

Melina Schuh (1,451 words) [view diff] exact match in snippet view article find links to article

Blayney, Martyn; Elder, Kay; Schuh, Melina (15 December 2015). "Sister kinetochore splitting and precocious disintegration of bivalents could explain the

Microtubule associated scaffold protein 2 (343 words) [view diff] exact match in snippet view article find links to article

TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosis". J. Biol

KNOP1 (917 words) [view diff] exact match in snippet view article find links to article

protein complexes are a core component of the end-on attachment sites for kinetochore microtubules. SMAP (Small acidic protein family) is found in eukaryotes

NFE2L1 (3,628 words) [view diff] exact match in snippet view article find links to article

expression of genes encoding components of the spindle assembly and kinetochore. NFE2L1 has also been shown to sense and respond to excess cholesterol

UBTF (2,151 words) [view diff] exact match in snippet view article find links to article

PMID 8641287. Pluta AF, Earnshaw WC (1996). "Specific interaction between human kinetochore protein CENP-C and a nucleolar transcriptional regulator". J. Biol. Chem

CCDC190 (2,087 words) [view diff] exact match in snippet view article find links to article

and functional organization of the Ska complex, a key component of the kinetochore-microtubule interface". Molecular Cell. 46 (3): 274–86. doi:10.1016/j

TMP-HTag (450 words) [view diff] exact match in snippet view article find links to article

David M.; Lampson, Michael A. (October 2017). "Optogenetic control of kinetochore function". Nature Chemical Biology. 13 (10): 1096–1101. doi:10.1038/nchembio

Paul Khavari (1,802 words) [view diff] exact match in snippet view article find links to article

Z; Khavari, Paul A (October 2014). "Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma". Nature Genetics. 46

AMPA receptor (8,584 words) [view diff] exact match in snippet view article find links to article

Fukagawa, Tatsuo; Cheeseman, Iain M. (April 2011). "Induced Ectopic Kinetochore Assembly Bypasses the Requirement for CENP-A Nucleosomes". Cell. 145

Condensin (11,490 words) [view diff] exact match in snippet view article find links to article

component NCAPG2 regulates microtubule-kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores". Nat Commun. 5: 4588. Bibcode:2014NatCo

Aurora inhibitor (1,118 words) [view diff] exact match in snippet view article find links to article

small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint"

Nucleolar and spindle associated protein 1 (577 words) [view diff] exact match in snippet view article find links to article

SY, Chen ES, Liou YC (January 2016). "NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity". Sci Rep

CHAMP1-associated intellectual disability syndrome (1,375 words) [view diff] exact match in snippet view article find links to article

et al. (January 2011). "CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment". The EMBO Journal. 30 (1): 130–44. doi:10.1038/emboj

C1orf112 (1,625 words) [view diff] exact match in snippet view article find links to article

McEwen BF (February 2005). "Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites". Molecular

Meier-Gorlin syndrome (1,474 words) [view diff] exact match in snippet view article find links to article

also participates in MMR during DNA replication. Also, CDT1 stabilizes kinetochore-microtubule interactions during M phase. ORC1 regulates centrosome and

FAM98A (2,469 words) [view diff] exact match in snippet view article find links to article

Phyre2 found the most similar protein to be the human protein NDC80 kinetochore complex component, a nuclear protein that binds to microtubules. FAM98A

Cyclin B3 (1,705 words) [view diff] exact match in snippet view article find links to article

elegans embryos where it again governs chromatid separation as well as kinetochore and microtubule assembly. It additionally appears to drive rapid mitosis

Biomolecular condensate (10,043 words) [view diff] exact match in snippet view article find links to article

Ballister, D. M.Chenoweth, and M. A. Lampson, "Optogenetic control of kinetochore function," Nature Chemical Biology, vol. 13, pp. 1096–1101, Aug 2017

Barbulanympha (1,168 words) [view diff] exact match in snippet view article find links to article

(1978-06-01). "Mitosis in Barbulanympha. I. Spindle structure, formation, and kinetochore engagement". Journal of Cell Biology. 77 (3): 638–654. doi:10.1083/jcb

Glossary of cellular and molecular biology (M–Z) (30,529 words) [view diff] exact match in snippet view article

replicated chromosomes align along the equator of the cell, with each kinetochore attached to the mitotic spindle. methylation The covalent attachment

Stress granule (12,583 words) [view diff] exact match in snippet view article find links to article

G-patch domain-containing protein 2 SUGT1 SUGT1 SGT1 Homolog, MIS12 Kinetochore Complex Assembly Cochaperone SUN1 SUN1 SUN domain-containing protein